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基于证据的紧急临时心脏起搏(金属丝电极电刺激)分析

Evidence-Based Analysis of the Emergency Temporary Cardiac Pacing (Electrical Stimulation from Metal Wire Electrode).

作者信息

Liu Meng, Lin Xuming, Tan Qiaoyin, Han Xiaotong

机构信息

Emergency Department, Hunan Provincial People's Hospital (The First-Affiliated Hospital of Hunan Normal University), Changsha 410005, Hunan, China.

Electromyogram Department, Hunan Province Hospital of Chinese Medicine (The Second-Affiliate Hospital of Hunan University of Chiniese Medicine), Changsha 410005, China.

出版信息

Bioinorg Chem Appl. 2021 Aug 25;2021:5677598. doi: 10.1155/2021/5677598. eCollection 2021.

DOI:10.1155/2021/5677598
PMID:34484317
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8413046/
Abstract

The patient's Cr (creatinine), BUN (blood urea nitrogen), HBG (hemoglobin), VT (ventricular tachycardia), pacing frequency, puncture point, emergency to permanent pacing time, pacing current (mA), pacing threshold current (mA), and admission diagnosis data were collected. The data were subjected to frequency statistics, curve regression analysis, PLS regression analysis, adjustment analysis, chi-square test, ridge regression analysis, discriminant analysis, negative binomial regression analysis, Poisson regression analysis, and stepwise regression analysis. Some findings include the following: (1) Cr has a significant positive effect on HBG, and BUN has a significant negative effect on HBG. (2) VT has a negative correlation with age and a positive correlation with CK-MB and CK (creatinine kinase). (3) Myocarditis has a negative correlation with age and a significant positive correlation with CTnI (cardiac troponin I). (4) AST (aspartate transaminase) and ALT (alanine aminotransferase) have a significant positive impact on DDI (D-dimer), while CTnI has a significant negative impact on DDI. MYO (myoglobin) has no impact relationship to DDI. (5) ALT has a significant positive relationship with APTT (partial thromboplastin time). (6) Alb (albumin) and TBIL (total bilirubin) have a significant positive effect on PLT (platelet) count, while pro-BNP (B-type natriuretic peptide) and MYO have a significant negative effect on PLT. (7) CK has a significant positive effect on INR (international normalized ratio). (8) The relationship between sinus node dysfunction and VT significantly affect the pacing frequency (beats/minute). For third-degree atrioventricular block, different samples of sinus node dysfunction showed significant differences. (9) There is a significant positive correlation between pacing current (mA) and pacing threshold current (mA). (10) There was a significant positive correlation between perceived voltage (mV) and the time from emergency to permanent pacing. Admission diagnosis has a significant positive impact on the time from emergency to permanent pacing. The change (increase) in time from emergency to permanent pacing was 1.137-fold when an additional condition was diagnosed on admission.

摘要

收集患者的肌酐(Cr)、血尿素氮(BUN)、血红蛋白(HBG)、室性心动过速(VT)、起搏频率、穿刺点、紧急起搏至永久起搏时间、起搏电流(mA)、起搏阈值电流(mA)以及入院诊断数据。对这些数据进行频率统计、曲线回归分析、偏最小二乘回归分析、调整分析、卡方检验、岭回归分析、判别分析、负二项回归分析、泊松回归分析和逐步回归分析。部分研究结果如下:(1)Cr对HBG有显著正效应,BUN对HBG有显著负效应。(2)VT与年龄呈负相关,与肌酸激酶同工酶(CK-MB)和肌酸激酶(CK)呈正相关。(3)心肌炎与年龄呈负相关,与心肌肌钙蛋白I(CTnI)呈显著正相关。(4)天门冬氨酸氨基转移酶(AST)和丙氨酸氨基转移酶(ALT)对D-二聚体(DDI)有显著正影响,而CTnI对DDI有显著负影响。肌红蛋白(MYO)与DDI无影响关系。(5)ALT与活化部分凝血活酶时间(APTT)有显著正相关关系。(6)白蛋白(Alb)和总胆红素(TBIL)对血小板(PLT)计数有显著正效应,而脑钠肽前体(pro-BNP)和MYO对PLT有显著负效应。(7)CK对国际标准化比值(INR)有显著正效应。(8)窦房结功能障碍与VT之间的关系显著影响起搏频率(次/分钟)。对于三度房室传导阻滞,不同样本的窦房结功能障碍存在显著差异。(9)起搏电流(mA)与起搏阈值电流(mA)之间存在显著正相关。(10)感知电压(mV)与紧急起搏至永久起搏时间之间存在显著正相关。入院诊断对紧急起搏至永久起搏时间有显著正影响。入院时多诊断出一种病症,紧急起搏至永久起搏时间的变化(增加)为1.137倍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b786/8413046/2123ad3d0eea/BCA2021-5677598.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b786/8413046/e8eec2c1516f/BCA2021-5677598.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b786/8413046/2123ad3d0eea/BCA2021-5677598.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b786/8413046/e8eec2c1516f/BCA2021-5677598.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b786/8413046/2123ad3d0eea/BCA2021-5677598.002.jpg

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