Huynh V A, Janssen C, Beaumier L
Service d'allergologie, Centre Hospitalier Annecy-Genevois, 1, avenue de l'Hôpital, 74370 Epagny Metz-Tessy, France.
Service Infectiologie, Centre Hospitalier Annecy-Genevois, 1, avenue de l'Hôpital, 74370 Epagny Metz-Tessy, France.
Rev Fr Allergol (2009). 2022 May;62(4):431-434. doi: 10.1016/j.reval.2021.07.007. Epub 2021 Aug 28.
Vaccination is the most efficient way to fight the Covid epidemic. However, suspicion of severe hypersensitivity to PEG (PolyEthylen Glycol) usually constitutes a vaccine contraindication. We report the case of a patient with a proven allergy to PEG and skin sensitization to the COMIRNATY vaccine (PEG in its composition). He was able to benefit from the vaccine under the 5-step desensitization protocol. Conclusions: Specific allergological management should be offered to patients suspected of severe hypersensitivity to PEG and other vaccine excipients. We propose a solution for Comirnaty administration for patients with a proven severe allergy to PEG.
接种疫苗是对抗新冠疫情最有效的方法。然而，怀疑对聚乙二醇（PEG）有严重超敏反应通常构成疫苗接种禁忌。我们报告了一例对PEG过敏且对COMIRNATY疫苗（其成分中含有PEG）皮肤致敏的患者病例。他能够在五步脱敏方案下接种该疫苗。结论：对于怀疑对PEG和其他疫苗辅料有严重超敏反应的患者，应提供特定的变应性疾病管理。我们为已证实对PEG严重过敏的患者提出了COMIRNATY疫苗的接种解决方案。
