From the Nagoya Eye Clinic, Nagoya, Aichi, Japan (Nishida, Kojima, Kataoka, Isogai, Yoshida, Nakamura); the Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan (Kojima).
J Cataract Refract Surg. 2022 May 1;48(5):604-610. doi: 10.1097/j.jcrs.0000000000000804.
To create an equation for predicting the trabecular iris angle (TIA) and to verify its accuracy after implantable collamer lens (ICL) implantation.
Nagoya Eye Clinic, Nagoya, Japan.
Retrospective evaluation of a screening approach.
174 eyes (174 patients) that underwent ICL implantation were included. Patients were randomly assigned to the prediction equation group (116 eyes) or verification group (58 eyes). Anterior segment optical coherence tomography (AS-OCT) (CASIA2 TOMEY) was performed before and 3 months after ICL surgery. For the prediction group, a prediction equation was created with the preoperative AS-OCT parameters and ICL size as independent variables and the postoperative anterior chamber depth (ACD) as the dependent variable. Then, by applying the predicted post-ACD and preoperative AS-OCT parameters as independent variables and TIA after ICL surgery as the dependent variable, a prediction equation was created to predict the postoperative TIA (post-TIA) after ICL surgery. Each prediction equation was created using stepwise multiple regression analysis, and its accuracy was verified by a Bland-Altman plot in the verification group.
The explanatory variables (standardized partial regression coefficient) selected in the post-TIA prediction equation were post-ACD (0.629), TIA750 (0.563), iris curvature (0.353), pupil diameter (-0.281), iris area (-0.249), and trabecular iris space area 250 (-0.171) (R2 = 0.646) (n = 116). There were no clinically significant systematic errors between measured and predictive post-TIA values in the verification group (n = 58). The mean absolute prediction error was 3.43 ± 2.22 degrees.
Post-TIA was accurately predicted from the predicted post-ACD and other preoperative AS-OCT parameters.
建立预测小梁虹膜角度（TIA）的方程，并验证其在可植入Collamer 透镜（ICL）植入术后的准确性。
日本名古屋眼科诊所。
筛选方法的回顾性评估。
纳入 174 只眼（174 例患者）接受 ICL 植入术。患者随机分为预测方程组（116 只眼）和验证组（58 只眼）。术前和 ICL 术后 3 个月进行眼前节光学相干断层扫描（AS-OCT）（CASIA2 TOMEY）。对于预测组，使用术前 AS-OCT 参数和 ICL 大小作为自变量，术后前房深度（ACD）作为因变量创建预测方程。然后，通过应用预测的术后 ACD 和术前 AS-OCT 参数作为自变量，ICL 术后 TIA 作为因变量，创建预测 ICL 术后 TIA（术后 TIA）的预测方程。使用逐步多元回归分析创建每个预测方程，并在验证组中通过 Bland-Altman 图验证其准确性。
术后 TIA 预测方程中选择的解释变量（标准化偏回归系数）为术后 ACD（0.629）、TIA750（0.563）、虹膜曲率（0.353）、瞳孔直径（-0.281）、虹膜面积（-0.249）和小梁虹膜空间面积 250（-0.171）（R2=0.646）（n=116）。验证组（n=58）中，测量值与预测术后 TIA 值之间无临床显著系统误差。平均绝对预测误差为 3.43±2.22 度。
可从预测的术后 ACD 和其他术前 AS-OCT 参数准确预测术后 TIA。
