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儿童哮喘患者体重指数与哮喘的相互关系——分析性横断面研究。

Interrelationship between body mass index and asthma in children suffering from asthma-analytical cross-sectional study.

机构信息

Department of Pediatrics, College of Medicine, Majmaah University Majmaah, Saudi Arabia.

出版信息

Eur Rev Med Pharmacol Sci. 2021 Aug;25(16):5208-5214. doi: 10.26355/eurrev_202108_26534.

Abstract

OBJECTIVE

Bronchial asthma and obesity are correlated diseases that are highly prevalent among children. The effect of increased body mass index (BMI), aggravating asthma, is currently controversial in this group. The aim of this study is to determine the association between Body Mass Index and severity of asthma among obese children with asthma and normal-weight children with asthma in Riyadh, Saudi Arabia.

PATIENTS AND METHODS

Data from a cross-sectional analysis of 64 participants from Riyadh, Saudi Arabia, were analyzed. Symptoms were assessed through children's and caregivers' responses to a pretested questionnaire. Grouping of children into obese (18) and non-obese (46) was based on their body mass index (BMI) percentile. Association between obesity and final asthma score was estimated by chi-square test using SPSS software and p-value set at 0.005.

RESULTS

The mean age was 10.13 ± 2.54 years (ranged 5 to 14), and the majority, 46 (71.88%), were boys. Most of the participants, 46 (71.88%), were normal to underweight and 18 (28.13%) were overweight or obese. Most of the children, 35 (54.69%), complained of cough because of asthma sometimes. Out of 64 participants, 21 (32.81%) had uncontrolled asthma, and 43 (67.19%) had controlled asthma calculated using a questionnaire. Out of 46 non-obese children with asthma, 7 (15.22%) had uncontrolled asthma, and out of 18 obese children with asthma, 14 (77.78%) had uncontrolled asthma, and the difference in the proportion of Asthma severity was significant statistically across the groups (p-value <0.001).

CONCLUSIONS

Poor control of asthma symptoms was significantly higher in both obese and normal-weight children with asthma.

摘要

目的

支气管哮喘和肥胖是两种高度流行于儿童的相关疾病。目前,对于肥胖儿童哮喘患者而言,体重指数(BMI)增加会加重哮喘的影响,这一观点仍存在争议。本研究旨在确定在沙特阿拉伯利雅得,肥胖哮喘儿童和正常体重哮喘儿童的 BMI 与哮喘严重程度之间的关系。

患者和方法

对来自沙特阿拉伯利雅得的 64 名参与者进行了横断面分析,通过儿童和护理人员对预测试问卷的回答来评估症状。通过他们的 BMI 百分位值将儿童分为肥胖(18 人)和非肥胖(46 人)两组。使用 SPSS 软件的卡方检验估计肥胖与最终哮喘评分之间的关联,p 值设为 0.005。

结果

平均年龄为 10.13 ± 2.54 岁(范围为 5 至 14 岁),其中 46 人(71.88%)为男孩。大多数参与者(46 人,71.88%)为正常体重至体重不足,18 人(28.13%)超重或肥胖。大多数儿童(35 人,54.69%)因哮喘而有时咳嗽。在 64 名参与者中,21 人(32.81%)哮喘未得到控制,43 人(67.19%)通过问卷计算哮喘得到控制。在 46 名非肥胖哮喘儿童中,有 7 人(15.22%)哮喘未得到控制,在 18 名肥胖哮喘儿童中,有 14 人(77.78%)哮喘未得到控制,两组哮喘严重程度的比例差异具有统计学意义(p 值<0.001)。

结论

肥胖和非肥胖哮喘儿童的哮喘症状控制不佳的比例明显更高。

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