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四肢创伤中碳纤维增强聚醚醚酮(CFR-PEEK)板的骨折固定:今日证据。

Fracture fixation in extremity trauma with carbon fiber-reinforced polyetheretherketone (CFR-PEEK) plates: evidence today.

机构信息

Academic Department of Trauma and Orthopaedic Surgery, School of Medicine, University of Leeds, Leeds, UK.

Invibio Biomaterial Solutions Ltd, Hillhouse International, Thornton-Cleveleys, Lancashire, UK.

出版信息

Eur J Trauma Emerg Surg. 2022 Jun;48(3):2387-2406. doi: 10.1007/s00068-021-01778-x. Epub 2021 Sep 6.

Abstract

PURPOSE

To compare the CFR-PEEK plates with conventional plates in fracture fixation with regards to clinical and radiological outcomes and complications.

METHODS

A systematic literature search was conducted in four online databases independently by two reviewers using the Cochrane methodology for systematic reviews. The identified relevant studies were assessed against predetermined inclusion/exclusion criteria. Independent data extraction and assessment of risk of bias and study quality was carried out.

RESULTS

Nine studies (patient n = 361) out of 6594 records were included for analysis: 2 RCTs (n = 63), 3 prospective cohort studies (n = 151), and 4 retrospective cohort studies (n = 147). Studies were grouped per anatomic area of fixation. Four studies (n = 200) examined fixation of proximal humerus fractures. Two studies (n = 74) examined fixation of distal radius fractures. Two studies (n = 53) assessed outcomes of fixation of distal femur fractures. One study (n = 87) assessed the outcomes of fixation of ankle fractures. All nine studies reported very high union rates (from 91% in distal femur to 100% in upper limb) for the CFR-PEEK plate groups and low complication rates. There was no significant difference in clinical outcomes, and rate of complications as compared to the conventional plate groups.

CONCLUSION

CFR-PEEK plates have high union rates in extremity fracture fixation similar to conventional plates with comparable good clinical outcomes and a very low and comparable rate of complications. Considering their advantages, CFR-PEEK plates seem to be valid alternative to conventional plating.

摘要

目的

比较 CFR-PEEK 板与传统板在骨折固定中的临床和影像学结果及并发症。

方法

两名评审员采用 Cochrane 系统评价方法,独立在四个在线数据库中进行系统文献检索。根据预定的纳入/排除标准对确定的相关研究进行评估。独立进行数据提取和风险偏倚及研究质量评估。

结果

在 6594 条记录中,有 9 项研究(患者 n=361)纳入分析:2 项 RCT(n=63),3 项前瞻性队列研究(n=151)和 4 项回顾性队列研究(n=147)。根据固定解剖区域对研究进行分组。4 项研究(n=200)研究了肱骨近端骨折的固定。2 项研究(n=74)研究了桡骨远端骨折的固定。2 项研究(n=53)评估了股骨远端骨折固定的结果。1 项研究(n=87)评估了踝关节骨折固定的结果。CFR-PEEK 板组的所有 9 项研究均报告了非常高的愈合率(从股骨远端的 91%到上肢的 100%)和低并发症率。与传统板组相比,CFR-PEEK 板在临床结果和并发症发生率方面没有显著差异。

结论

CFR-PEEK 板在四肢骨折固定中的愈合率与传统板相似,具有相似的良好临床结果,且并发症发生率非常低且相似。考虑到它们的优势,CFR-PEEK 板似乎是传统接骨板的有效替代物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1684/9192460/6e9d31a41b17/68_2021_1778_Fig1_HTML.jpg

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