Institute of Public Health & Social Sciences, Khyber Medical University, Peshawar, Pakistan.
Institute of Basic Medical Sciences, Khyber Medical University, Peshawar, Pakistan.
J Ayub Med Coll Abbottabad. 2021 Jul-Sep;33(3):519-522.
Protection against SARS-CoV-2 in infected individuals of COVID-19 is lacking. We report a case series of repeated infections of SARS-CoV-2.
A total of 12 patients were identified with repeated infections for SARS-CoV-2 from 25 April 2020 to 16 March 2021 from Pakistan. Repeated infection was defined as diagnosis of the SARS-CoV-2 with real-time reverse transcriptase-polymerase chain reaction (RT-PCR) tests in the first and second phase of infection after complete recovery from the first phase of infection with a negative RT-PCR.
Of the 12 participants, 75% (n=9) were male and mean age of the participants were 40.1±9.7 years. Mean duration between the first and second phase of infection was 184±68.9 days. Patients presenting with mild infection in the first phase largely developed moderate to severe infection in the second phase. None of them were vaccinated.
The pandemic of COVID-19 is on the rise and repeated infection from SARS-CoV-2 is occurring.
COVID-19 感染者对 SARS-CoV-2 缺乏保护。我们报告了一系列重复感染 SARS-CoV-2 的病例。
从 2020 年 4 月 25 日至 2021 年 3 月 16 日，我们从巴基斯坦共发现 12 例重复感染 SARS-CoV-2 的患者。重复感染的定义为在首次感染完全康复后，通过实时逆转录-聚合酶链反应（RT-PCR）检测，在第一和第二阶段感染中诊断出 SARS-CoV-2，且第一次 RT-PCR 为阴性。
12 名参与者中，75%（n=9）为男性，参与者的平均年龄为 40.1±9.7 岁。第一阶段和第二阶段之间的平均间隔时间为 184±68.9 天。在第一阶段感染时表现为轻症的患者，在第二阶段大多发展为中重度感染。他们均未接种疫苗。
COVID-19 大流行正在加剧，且 SARS-CoV-2 重复感染正在发生。
