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感染与青光眼。

Infections and glaucoma.

机构信息

Department of Ophthalmology, University of North Carolina-Chapel Hill School of Medicine, Chapel Hill, NC, USA.

Department of Ophthalmology, Duke University School of Medicine, Durham, NC, USA.

出版信息

Surv Ophthalmol. 2022 May-Jun;67(3):637-658. doi: 10.1016/j.survophthal.2021.08.009. Epub 2021 Sep 4.

DOI:10.1016/j.survophthal.2021.08.009
PMID:34487741
Abstract

Glaucoma is an intraocular pressure-related ophthalmic disease with multiple causes that results in an optic neuropathy and vision loss. Intraocular pressure elevation is among its strongest risk factors. While glaucoma is mostly primary in etiology, secondary glaucoma is not infrequent. Recognizing its cause is imperative, since treatment is often different depending on the pathophysiologic mechanism. Numerous clinically relevant ophthalmic infections can result in robust inflammatory responses that may result in pressure elevation or intraocular anatomic configurations that predispose to pressure elevation. Knowing the mechanisms by which these infections can lead to glaucoma is critical in treating, and we consolidate what is currently known in regards to how infectious diseases lead to glaucoma.

摘要

青光眼是一种与眼内压相关的眼科疾病,病因多样,可导致视神经病变和视力丧失。眼内压升高是其最强的危险因素之一。虽然青光眼在病因上主要是原发性的,但继发性青光眼也不少见。认识其病因至关重要,因为治疗方法常常因病理生理机制而异。许多与临床相关的眼部感染可引起强烈的炎症反应,导致眼压升高或易导致眼压升高的眼内解剖结构。了解这些感染导致青光眼的机制对于治疗至关重要,我们总结了目前已知的传染病导致青光眼的方式。

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1
Infections and glaucoma.感染与青光眼。
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2
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2
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Identifying Hub Genes for Glaucoma based on Bulk RNA Sequencing Data and Multi-machine Learning Models.
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Curr Med Chem. 2024;31(42):7059-7071. doi: 10.2174/0109298673283658231130104550.
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Viral infections and pathogenesis of glaucoma: a comprehensive review.病毒感染与青光眼发病机制:全面综述。
Clin Microbiol Rev. 2023 Dec 20;36(4):e0005723. doi: 10.1128/cmr.00057-23. Epub 2023 Nov 15.
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Association between dietary calcium, potassium, and magnesium consumption and glaucoma.饮食钙、钾和镁的摄入与青光眼的关系。
PLoS One. 2023 Oct 18;18(10):e0292883. doi: 10.1371/journal.pone.0292883. eCollection 2023.
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