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湄公血吸虫和间插血吸虫在小鼠体内的肺部迁移模式。

Lung-migration patterns of Schistosoma mekongi and S. spindale in mouse.

作者信息

Janecharut T, Usawattanakul W, Sornmani S, Kitikoon V

机构信息

Department of Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

出版信息

Southeast Asian J Trop Med Public Health. 1987 Dec;18(4):484-7.

PMID:3448775
Abstract

Two groups of laboratory-bred Swiss albino mice were used to study the lung-migration patterns of Schistosoma mekongi and S. spindale. The first group was individually infected with 100 S. mekongi cercariae by hair-looping application on shaved abdomen. The latter group was individually exposed to 500 S. spindale cercariae by tail immersion. Each group of these infected mice was then divided into subgroups. The number of schistosomulae was determined using a lung recovery assay starting from the second day after infection and continuing for 15 consecutive days. The results revealed a sharp peak of both S. mekongi and S. spindale on the fifth day post cercarial infection.

摘要

两组实验室饲养的瑞士白化小鼠被用于研究湄公血吸虫和梭形血吸虫的肺部迁移模式。第一组通过在剃毛的腹部用发圈涂抹法单独感染100条湄公血吸虫尾蚴。后一组通过尾部浸入法单独暴露于500条梭形血吸虫尾蚴。然后将每组感染的小鼠分成亚组。从感染后的第二天开始,使用肺部回收试验确定童虫数量,并连续进行15天。结果显示,在尾蚴感染后的第五天,湄公血吸虫和梭形血吸虫的数量均出现急剧峰值。

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