CREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290-Université de Montpellier, Montpellier, France.
CREEC/CANECEV (CREES), MIVEGEC, Unité Mixte de Recherches, IRD 224-CNRS 5290-Université de Montpellier, Montpellier, France.
Sci Total Environ. 2022 Jan 10;803:149923. doi: 10.1016/j.scitotenv.2021.149923. Epub 2021 Aug 26.
While it is often assumed that oncogenic processes in metazoans can influence species interactions, empirical evidence is lacking. Here, we use the cnidarian Hydra oligactis to experimentally explore the consequences of tumor associated phenotypic alterations for its predation ability, relationship with commensal ciliates and vulnerability to predators. Unexpectedly, hydra's predation ability was higher in tumorous polyps compared to non-tumorous ones. Commensal ciliates colonized preferentially tumorous hydras than non-tumorous ones, and had a higher replication rate on the former. Finally, in a choice experiment, tumorous hydras were preferentially eaten by a fish predator. This study, for the first time, provides evidence that neoplastic growth has the potential, through effect(s) on host phenotype, to alter biotic interactions within ecosystems and should thus be taken into account by ecologists.
虽然人们通常认为后生动物的致癌过程会影响物种间的相互作用，但缺乏经验证据。在这里，我们使用刺胞动物 Hydra oligactis 来实验性地探索与肿瘤相关的表型改变对其捕食能力、与共生纤毛虫的关系和对捕食者的易感性的影响。出乎意料的是，与非肿瘤息肉相比，肿瘤息肉的捕食能力更高。共生纤毛虫优先定植于肿瘤息肉 Hydra 上，而不是非肿瘤息肉上，并且在前者上的复制率更高。最后，在选择实验中，鱼类捕食者优先捕食肿瘤息肉 Hydra。这项研究首次提供了证据，表明肿瘤生长有可能通过对宿主表型的影响来改变生态系统内的生物相互作用，因此生态学家应该考虑到这一点。
