《基于功能信念的酒精使用问卷（FBAQ）在清迈大学本科生中的预筛查能力：一项外部验证研究》
Pre-screening Ability of the Functional-Belief-Based Alcohol Use Questionnaire (FBAQ) among Chiang Mai University Undergraduates: An External Validation Study.
机构信息
Department of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros, Sriphum, Mueng, Chiang Mai 50200, Thailand; Center for Clinical Epidemiology and Clinical Statistics, Faculty of Medicine, Chiang Mai University, 110 Intawaroros, Sriphum, Mueng, Chiang Mai 50200, Thailand; Muskuloskeletal Science and Translational Research (MSTR), Chiang Mai University, 110 Intawaroros, Sriphum, Mueng, Chiang Mai 50200, Thailand.
Department of Family Medicine, Faculty of Medicine, Chiang Mai University, 110 Intawaroros, Sriphum, Mueng, Chiang Mai 50200, Thailand.
出版信息
Drug Alcohol Depend. 2021 Oct 1;227:109002. doi: 10.1016/j.drugalcdep.2021.109002. Epub 2021 Aug 28.
BACKGROUND
High-risk drinking behavior is common in university students, which often leads to negative consequences. Several standard screening tools to identify high-risk drinkers have been validated in this domain. However, most tools rely on drinking frequency and require standard drink calculations. The Functional-Belief-Based Alcohol use Questionnaire (FBAQ) was recently proposed as a pre-screening tool for high-risk drinkers in the young adult population. We aimed to validate the pre-screening accuracy of the FBAQ when applied to external data of university undergraduates.
METHODS
Data from two prospective cross-sectional surveys of Chiang Mai University undergraduates were used for validation of the FBAQ. A high-risk drinker was defined as a person with the 12-month AUDIT score ≥ 8. Pre-screening performance and accuracy indices were presented separately for dataset I, dataset II, and the combined dataset. The pooled area under the receiver operating characteristic curve (AuROC), sensitivity, and specificity were estimated using individual patient data meta-analysis methods.
RESULTS
From the two datasets, 1641 students were included, 811 students in 2019 and 830 students in 2020. Of these, 387 (23.6 %) students were classified as high-risk drinkers. The combined AuROC of the FBAQ score was 0.83 (95 %CI 0.75-0.92) in discriminating high-risk drinkers. The pooled sensitivity and specificity at the FBAQ score cutoff ≥ 6 were 92.8 % (95 %CI 88.0-95.7 %) and 51.6 % (95 %CI 41.1-62.0 %).
CONCLUSIONS
In this external validation, the FBAQ shows excellent discriminative ability and is proven to be highly sensitive in detecting high-risk drinkers among Chiang Mai University undergraduates. Therefore, incorporating the FBAQ as a pre-screening tool to the AUDIT could make the initiation of the screening process easier and reduce extensive AUDIT evaluations in students with low risk.
背景
高危饮酒行为在大学生中很常见，这往往会导致负面后果。已经有几种标准的筛查工具被验证可以用于识别高危饮酒者。然而，大多数工具都依赖于饮酒频率，并需要进行标准饮品的计算。功能性-信念为基础的酒精使用问卷（FBAQ）最近被提出作为年轻成年人中高危饮酒者的预筛工具。我们旨在验证 FBAQ 在应用于大学生的外部数据时的预筛准确性。
方法
使用来自清迈大学本科生的两项前瞻性横断面调查的数据来验证 FBAQ。高危饮酒者定义为 AUDIT 评分在 12 个月内≥8 分的人。分别为数据集 I、数据集 II 和合并数据集呈现预筛性能和准确性指数。使用个体患者数据荟萃分析方法估计合并的接受者操作特征曲线（AuROC）下面积、敏感性和特异性。
结果
从两个数据集中共纳入了 1641 名学生，其中 2019 年有 811 名学生，2020 年有 830 名学生。其中，387 名（23.6%）学生被归类为高危饮酒者。FBAQ 评分在区分高危饮酒者方面的合并 AuROC 为 0.83（95%CI 0.75-0.92）。FBAQ 评分≥6 时的合并敏感性和特异性分别为 92.8%（95%CI 88.0-95.7%）和 51.6%（95%CI 41.1-62.0%）。
结论
在这项外部验证中，FBAQ 显示出优异的区分能力，并且证明在检测清迈大学本科生中的高危饮酒者时具有高度敏感性。因此，将 FBAQ 作为 AUDIT 的预筛工具可以使筛查过程更容易启动，并减少对低风险学生的广泛 AUDIT 评估。
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