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强迫症的集中暴露疗法能改善失眠症状吗?一项随机对照试验的结果

Does Concentrated Exposure Treatment for Obsessive-Compulsive Disorder Improve Insomnia Symptoms? Results From a Randomized Controlled Trial.

作者信息

Hagen Kristen, Nordahl Håkon, Launes Gunvor, Kvale Gerd, Öst Lars-Göran, Hystad Sigurd, Hansen Bjarne, Solem Stian

机构信息

Department of Psychiatry, Molde Hospital, Møre og Romsdal Hospital Trust, Molde, Norway.

Bergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, Norway.

出版信息

Front Psychiatry. 2021 Aug 19;12:625631. doi: 10.3389/fpsyt.2021.625631. eCollection 2021.

DOI:10.3389/fpsyt.2021.625631
PMID:34489744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8417230/
Abstract

Insomnia is a substantial problem in patients with obsessive-compulsive disorder (OCD). There is, however, a lack of studies investigating changes in concurrent symptoms of insomnia in OCD after concentrated treatment. A recent randomized controlled trial randomized participants to the Bergen 4-day treatment (B4DT, = 16), or 12 weeks of unguided self-help (SH, = 16), or waitlist (WL, = 16). Patients from the SH- and WL-group who wanted further treatment after the 12 weeks were then offered the B4DT (total of 42 patients treated with the B4DT). There were no significant differences in symptoms of insomnia between the conditions at post-treatment, but a significant moderate improvement at 3-month follow-up for patients who received the B4DT. Insomnia was not associated with OCD-treatment outcome, and change in symptoms of insomnia was mainly related to changes in depressive symptoms. The main conclusion is that concentrated exposure treatment is effective irrespective of comorbid insomnia, and that insomnia problems are moderately reduced following treatment.

摘要

失眠是强迫症(OCD)患者面临的一个重大问题。然而,目前缺乏关于集中治疗后强迫症患者失眠并发症状变化的研究。最近一项随机对照试验将参与者随机分为接受卑尔根4天治疗组(B4DT,n = 16)、12周无指导自助组(SH,n = 16)或候补名单组(WL,n = 16)。12周后,SH组和WL组中希望进一步治疗的患者随后接受了B4DT(共有42名患者接受了B4DT治疗)。治疗后各条件下的失眠症状无显著差异,但接受B4DT治疗的患者在3个月随访时有显著的中度改善。失眠与强迫症治疗结果无关,失眠症状的变化主要与抑郁症状的变化有关。主要结论是,无论是否合并失眠,集中暴露治疗都是有效的,并且治疗后失眠问题会得到适度减轻。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dac/8417230/d0c77aa616f4/fpsyt-12-625631-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dac/8417230/d0c77aa616f4/fpsyt-12-625631-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5dac/8417230/d0c77aa616f4/fpsyt-12-625631-g0001.jpg

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本文引用的文献

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The Bergen 4-Day Treatment (B4DT) for Obsessive-Compulsive Disorder: Outcomes for Patients Treated After Initial Waiting List or Self-Help Intervention.卑尔根强迫症4日疗法(B4DT):初始等待名单或自助干预后接受治疗患者的治疗结果
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2
A Randomized Controlled Trial of Concentrated ERP, Self-Help and Waiting List for Obsessive- Compulsive Disorder: The Bergen 4-Day Treatment.强迫症的集中式暴露反应预防疗法、自助疗法和等待列表对照的随机对照试验:卑尔根4天治疗法
Front Psychol. 2019 Nov 15;10:2500. doi: 10.3389/fpsyg.2019.02500. eCollection 2019.
3
基于微选择的集中跨诊断和跨学科团体治疗对抑郁和焦虑患者的疗效:一项先导研究。
BMC Psychiatry. 2024 May 14;24(1):361. doi: 10.1186/s12888-024-05786-0.
Sleep in obsessive-compulsive and related disorders: a selective review and synthesis.
强迫症及相关障碍中的睡眠:选择性综述与综合分析
Curr Opin Psychol. 2020 Aug;34:23-26. doi: 10.1016/j.copsyc.2019.08.018. Epub 2019 Aug 24.
4
When Improving Symptoms Is Not Enough-Is It Time for Next-Generation Interventions for Obsessive-Compulsive Disorder?当改善症状并不够时——是时候采用强迫症的下一代干预措施了吗?
JAMA Psychiatry. 2020 Jan 1;77(1):9-10. doi: 10.1001/jamapsychiatry.2019.2335.
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