Brayley J, Yellowlees P
Flinders Medical Centre, Bedford Park, SA.
Aust N Z J Psychiatry. 1987 Dec;21(4):605-7. doi: 10.3109/00048678709158930.
A 37-year-old woman with cerebral palsy and a rapid cycling bipolar affective disorder developed drowsiness and slurred speech when being treated with a combination of haloperidol and a low dose of carbamazepine. This effect occurred twice but did not appear when the patient was given carbamazepine alone at much higher doses. This suggests that some patients who appear intolerant of carbamazepine may still benefit from this drug if concomitant haloperidol therapy is ceased.
一名患有脑瘫和快速循环型双相情感障碍的37岁女性，在接受氟哌啶醇和低剂量卡马西平联合治疗时出现嗜睡和言语不清。这种情况发生了两次，但当患者单独服用高得多剂量的卡马西平时并未出现。这表明，一些看似不能耐受卡马西平的患者，如果停止同时使用氟哌啶醇治疗，可能仍能从该药中获益。
