Department of Applied Chemistry, Faculty of Engineering, Shizuoka University, 3-5-1 Johoku, Naka-ku, Hamamatsu 432-8561, Japan.
Division of Instrumental Analysis, Life Science Research Center, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
Chem Commun (Camb). 2021 Sep 28;57(77):9858-9861. doi: 10.1039/d1cc03833h.
A visible-light-induced desulfonylative Giese-type reaction has been developed. Essential to the success is the employment of Hantzsch ester to activate benzothiazole sulfones without any heavy-metal additives. Not only benzylic benzothiazole sulfones but also alkyl ones were viable substrates and reacted with electron-deficient alkenes and a propiol amide.
可见光诱导的去磺酰基 Giese 型反应已经被开发出来。成功的关键是使用 Hantzsch 酯激活苯并噻唑砜，而无需任何重金属添加剂。不仅苄基苯并噻唑砜，而且烷基苯并噻唑砜也是可行的底物，与缺电子的烯烃和丙炔酰胺反应。
