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通过N-芳基磺酰基羟胺与缺电子烯烃反应合成烷基芳基砜

Synthesis of Alkyl Aryl Sulfones via Reaction of N-Arylsulfonyl Hydroxyamines with Electron-Deficient Alkenes.

作者信息

Bin Yunhui, Hua Ruimao

机构信息

Department of Chemistry, Tsinghua University, Beijing 100084, China.

出版信息

Molecules. 2016 Dec 28;22(1):39. doi: 10.3390/molecules22010039.

DOI:10.3390/molecules22010039
PMID:28036047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6155654/
Abstract

Alkyl aryl sulfones were prepared in high yields via the reaction of -arylsulfonyl hydroxylamines with electron-deficient alkenes. These reactions have the advantages of simplicity, easily available starting materials and mild reaction conditions.

摘要

通过芳基磺酰基羟胺与缺电子烯烃的反应，以高收率制备了烷基芳基砜。这些反应具有操作简单、起始原料易于获得和反应条件温和的优点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/706bb203cc70/molecules-22-00039-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/bfe736a9360d/molecules-22-00039-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/abd1e672d836/molecules-22-00039-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/706bb203cc70/molecules-22-00039-sch002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/bfe736a9360d/molecules-22-00039-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/abd1e672d836/molecules-22-00039-sch001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb02/6155654/706bb203cc70/molecules-22-00039-sch002.jpg

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本文引用的文献

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Catalyst-Free Difunctionalization of Activated Alkenes in Water: Efficient Synthesis of β-Keto Sulfides and Sulfones.水中活化烯烃的无催化剂双官能团化：β-酮硫醚和砜的高效合成
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Efficient 2-sulfolmethyl quinoline formation from 2-methylquinolines and sodium sulfinates under transition-metal free conditions.
在无过渡金属条件下由2-甲基喹啉和亚磺酸钠高效合成2-磺甲基喹啉
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