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在北爱尔兰,对慢性胰腺炎继发糖尿病(DMsCP)患者队列中的糖尿病视网膜病变(DR)的筛查出席率、患病率和严重程度进行评估。

Screening attendance, prevalence and severity of diabetic retinopathy (DR) in a cohort of patients with diabetes mellitus secondary to chronic pancreatitis (DMsCP) in Northern Ireland.

机构信息

Belfast Ophthalmic Reading Centre, Centre for Public Health, Queen's University Belfast, Belfast, UK.

Ophthalmology Clinic, Department of Medicine and Science of Ageing, University G d'Annunzio Chieti-Pescara, Chieti, Italy.

出版信息

BMJ Open Diabetes Res Care. 2021 Sep;9(1). doi: 10.1136/bmjdrc-2021-002267.

Abstract

INTRODUCTION

This study investigated Northern Ireland Diabetic Eye Screening Programme (NIDESP) attendance and diabetic retinopathy (DR) prevalence/severity in patients with diabetes mellitus secondary to chronic pancreatitis (PwDMsCP).

RESEARCH DESIGN AND METHODS

Medical/NIDESP records for all PwDMsCP attending the pancreatic diabetes clinic were analyzed in 2017 (n=78) and 2019 (n=94).

RESULTS

Between 2017 and 2019, those without DR decreased (76% to 63%); mild non-proliferative DR (NPDR), severe NPDR and PDR were found in 30%, 2% and 5%, respectively (previously 18%, 4%, 2%); diabetic maculopathy (DMac) was present in 12% (previously 10%). There was no significant difference between worst-eye DR/DMac grade and HbA1c, gender, body mass index, pancreatitis etiology and screening attendance (p>0.05). Patients with proliferative DR had longer diabetes and pancreatitis duration than DR-free patients (both p=0.001).

CONCLUSIONS

DR prevalence was similar in PwDMsCP and patients with type 2 diabetes of similar disease duration. This work demonstrates the importance of reaching all patients for establishing DR severity reliably and to provide accessible, equitable care to PwDMsCP.

摘要

介绍

本研究调查了因慢性胰腺炎继发糖尿病(PwDMsCP)患者参与北爱尔兰糖尿病眼病筛查计划(NIDESP)的情况以及糖尿病视网膜病变(DR)的患病率/严重程度。

研究设计和方法

对 2017 年(n=78)和 2019 年(n=94)在胰腺糖尿病诊所就诊的所有 PwDMsCP 的医疗/NIDESP 记录进行了分析。

结果

在 2017 年至 2019 年间,无 DR 的患者比例下降(76%降至 63%);轻度非增生性 DR(NPDR)、重度 NPDR 和 PDR 的检出率分别为 30%、2%和 5%(之前分别为 18%、4%和 2%);糖尿病性黄斑病变(DMac)的检出率为 12%(之前为 10%)。最差眼 DR/DMac 分级与 HbA1c、性别、体重指数、胰腺炎病因和筛查参与率之间无显著差异(p>0.05)。增殖性 DR 患者的糖尿病和胰腺炎病程均长于无 DR 患者(均 p=0.001)。

结论

PwDMsCP 患者的 DR 患病率与病程相似的 2 型糖尿病患者相似。这项工作证明了为所有患者建立可靠的 DR 严重程度并为 PwDMsCP 提供可及、公平的护理的重要性。

相似文献

本文引用的文献

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Management of pancreatogenic diabetes: challenges and solutions.胰腺源性糖尿病的管理:挑战与解决方案
Diabetes Metab Syndr Obes. 2016 Aug 25;9:311-5. doi: 10.2147/DMSO.S99701. eCollection 2016.
4
Diagnosis and treatment of diabetes mellitus in chronic pancreatitis.慢性胰腺炎糖尿病的诊断与治疗。
World J Gastroenterol. 2013 Nov 14;19(42):7276-81. doi: 10.3748/wjg.v19.i42.7276.
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Diabetic retinopathy in chronic pancreatitis.慢性胰腺炎中的糖尿病性视网膜病变。
Arch Ophthalmol. 1971 Sep;86(3):245-50. doi: 10.1001/archopht.1971.01000010247001.

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