Foged Frederik, Rasmussen Iben Elmerdahl, Bjørn Budde Josephine, Rasmussen Rasmus Syberg, Rasmussen Villads, Lyngbæk Mark, Jønck Simon, Krogh-Madsen Rikke, Lindegaard Birgitte, Ried-Larsen Mathias, Berg Ronan Martin Griffin, Christensen Regitse Højgaard
Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark.
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
BMJ Open Sport Exerc Med. 2021 Sep 1;7(3):e001156. doi: 10.1136/bmjsem-2021-001156. eCollection 2021.
Many patients with COVID-19 suffer from persistent symptoms, many of which may potentially be reversed by high-intensity interval training (HIIT). Yet, the safety and tolerability of HIIT after COVID-19 is controversial. This study aimed to investigate the fidelity, tolerability and safety of three different HIIT protocols in individuals that had recently been hospitalised due to COVID-19.
The study was a randomised cross-over trial. We compared three supervised HIIT protocols (4×4, 6×1, 10-20-30) in 10 individuals recently discharged after hospitalisation for severe COVID-19. Each HIIT protocol had a duration of 38 min and was performed with a 1-week washout between them. Outcomes included adverse events, exercise training intensity and tolerability assessed by the Likert scale (1-10).
All 10 participants aged 61 (mean, SD 8) years (5 males) completed all three HIIT protocols with no adverse events. High intensities were achieved in all three protocols, although they differed in terms of time spent with a heart rate ≥85% of maximum (mean (SD); 4×4: 13.7 (6.4) min; 10-20-30: 12.1 (3.8) min; 6×1: 6.1 (5.6) min; p=0.03). The three protocols were all well tolerated with similar Likert scale scores (mean (SD); 4×4: 8 (2), 10-20-30: 8 (2), 6×1: 9 (2), p=0.72).
Our findings indicate that recently hospitalised individuals for severe COVID-19 may safely tolerate acute bouts of supervised HIIT as per protocol. This warrants future studies testing the potential of regular HIIT as a rehabilitation strategy in this context.
许多新冠病毒疾病（COVID-19）患者存在持续症状，其中许多症状可能通过高强度间歇训练（HIIT）得到缓解。然而，COVID-19康复后进行HIIT的安全性和耐受性仍存在争议。本研究旨在调查三种不同HIIT方案在近期因COVID-19住院的个体中的依从性、耐受性和安全性。
本研究为随机交叉试验。我们比较了三种有监督的HIIT方案（4×4、6×1、10 - 20 - 30），研究对象为10名因严重COVID-19住院后近期出院的个体。每个HIIT方案持续38分钟，方案之间有1周的洗脱期。观察指标包括不良事件、运动训练强度以及通过李克特量表（1 - 10）评估的耐受性。
所有10名参与者年龄为61岁（均值，标准差8）（5名男性），完成了所有三种HIIT方案，且无不良事件发生。所有三种方案均达到了高强度，尽管它们在心率≥最大心率85%的时间上有所不同（均值（标准差）；4×4：13.7（6.4）分钟；10 - 20 - 30：12.1（3.8）分钟；6×1：6.1（5.6）分钟；p = 0.03）。三种方案的耐受性均良好，李克特量表评分相似（均值（标准差）；4×4：8（2），10 - 20 - 30：8（2），6×1：9（2），p = 0.72）。
我们的研究结果表明，近期因严重COVID-19住院的个体可以按照方案安全耐受有监督的急性HIIT训练。这为未来研究在此背景下测试常规HIIT作为康复策略的潜力提供了依据。
