Nymand Stine Buus, Hartmann Jacob, Rasmussen Iben Elmerdahl, Iepsen Ulrik Winning, Ried-Larsen Mathias, Christensen Regitse Højgaard, Berg Ronan Martin Griffin
Centre for Physical Activity Research, Rigshospitalet, Copenhagen, Denmark.
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
BMJ Open Sport Exerc Med. 2023 Mar 8;9(1):e001486. doi: 10.1136/bmjsem-2022-001486. eCollection 2023.
High-intensity interval training (HIIT) during pulmonary rehabilitation in patients with chronic obstructive pulmonary disease (COPD) may alleviate the symptom burden, but the fidelity and tolerability of HIIT using long or short intervals in patients with COPD are unknown.
Twelve patients with moderate-to-severe COPD were included in a randomised cross-over pilot study. They completed two supervised HIIT protocols (4×4 and 10×1). To compare the two HIIT protocols, completed training amount, exercise intensity and perceived tolerability (assessed by a 10-point Likert scale) were integrated in a red-amber-green rating system. If a training session received a red ranking, it was considered unacceptable, if it received an amber ranking it was applicable with precautions, and if it received a green ranking it was considered feasible.
All patients completed the total training amount in both protocols. The 4×4 protocol resulted in three amber training sessions due to low perceived tolerability. The 10×1 protocol resulted in two red training sessions due to intensity reductions, and two amber training sessions because of low perceived tolerability. There was no statistical difference in perceived tolerability or time spent with an HR ≥85% of HR.
HIIT using longer intervals (4×4) at a relatively lower intensity resulted in higher fidelity expressed by fewer adjustments to the protocol, whereas there was no difference between protocols in perceived tolerance. The 4×4 protocol seems to have a higher fidelity compared with the 10×1 protocol in patients with moderate-to-severe COPD.
NCT05273684.
慢性阻塞性肺疾病（COPD）患者在肺康复期间进行高强度间歇训练（HIIT）可能会减轻症状负担，但COPD患者使用长间歇或短间歇进行HIIT的依从性和耐受性尚不清楚。
12例中重度COPD患者纳入一项随机交叉试验性研究。他们完成了两种有监督的HIIT方案（4×4和10×1）。为比较这两种HIIT方案，将完成的训练量、运动强度和感知耐受性（通过10分制李克特量表评估）整合到一个红-黄-绿评级系统中。如果一次训练获得红色评级，则认为不可接受；如果获得黄色评级，则表示适用但需注意；如果获得绿色评级，则认为可行。
所有患者均完成了两种方案的总训练量。4×4方案因感知耐受性低导致3次训练获得黄色评级。10×1方案因强度降低导致2次训练获得红色评级，因感知耐受性低导致2次训练获得黄色评级。在感知耐受性或心率≥85%时所花费的时间方面没有统计学差异。
在相对较低强度下使用较长间歇（4×4）的HIIT，因对方案的调整较少而表现出更高依从性，而两种方案在感知耐受性方面没有差异。在中重度COPD患者中，4×4方案似乎比10×1方案具有更高的依从性。
NCT05273684。
