• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

口腔癌患者在 COVID-19 大流行的第一年中的治疗延误和肿瘤大小。

Treatment delay and tumor size in patients with oral cancer during the first year of the COVID-19 pandemic.

机构信息

Department of Oral and Cranio-Maxillofacial Surgery, Heidelberg University Hospital, Heidelberg, Germany.

Institute of Medical Biometry and Informatics, Heidelberg University Hospital, Heidelberg, Germany.

出版信息

Head Neck. 2021 Nov;43(11):3493-3497. doi: 10.1002/hed.26858. Epub 2021 Sep 8.

DOI:10.1002/hed.26858
PMID:34494330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8652728/
Abstract

BACKGROUND

We set out to investigate how the ongoing coronavirus pandemic affected the size of tumors and the duration of treatment delay in patients with surgically treated oral squamous cell carcinoma.

METHODS

Patients with surgically treated oral cavity squamous cell carcinoma were assessed retrospectively and divided into two groups depending on when they had first presented at our clinic. Patients presenting from 2010 to 2019, that is, before COVID-19 onset (n = 566) were compared to patients presenting in 2020 (n = 58).

RESULTS

A total of 624 patients were included. Treatment delay was significantly longer in 2020 (median = 45 days) versus 2010-2019 (median = 35 days) (p = 0.004). We observed a higher pathological T classification in 2020 (p = 0.046), whereas pathological N classification was unchanged between groups (p = 0.843).

CONCLUSIONS

While extraordinary efforts continue to be made in the context of the pandemic, it is imperative that this does not lead to significant disadvantages for many people with oral cancer.

摘要

背景

我们旨在调查正在进行的冠状病毒大流行如何影响接受手术治疗的口腔鳞状细胞癌患者肿瘤大小和治疗延迟时间。

方法

回顾性评估接受手术治疗的口腔腔鳞状细胞癌患者,并根据他们首次就诊于我们诊所的时间将其分为两组。将 2010 年至 2019 年(即 COVID-19 发病前)就诊的患者(n=566)与 2020 年就诊的患者(n=58)进行比较。

结果

共纳入 624 例患者。2020 年的治疗延迟时间明显更长(中位数=45 天),而 2010-2019 年的治疗延迟时间(中位数=35 天)更短(p=0.004)。我们发现 2020 年的病理 T 分类更高(p=0.046),而两组之间的病理 N 分类没有变化(p=0.843)。

结论

虽然在大流行背景下继续做出非凡努力,但至关重要的是,这不会给许多口腔癌患者带来重大不利影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e529/8652728/cfa36f23d029/HED-43-3493-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e529/8652728/cfa36f23d029/HED-43-3493-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e529/8652728/cfa36f23d029/HED-43-3493-g001.jpg

相似文献

1
Treatment delay and tumor size in patients with oral cancer during the first year of the COVID-19 pandemic.口腔癌患者在 COVID-19 大流行的第一年中的治疗延误和肿瘤大小。
Head Neck. 2021 Nov;43(11):3493-3497. doi: 10.1002/hed.26858. Epub 2021 Sep 8.
2
Diagnostic Delays for Non-melanoma Skin Cancers in Renal Transplant Recipients during the COVID-19 Pandemic: What is Hiding Behind the Mask?COVID-19 大流行期间肾移植受者中非黑色素瘤皮肤癌的诊断延迟:口罩背后隐藏着什么?
Acta Dermatovenerol Croat. 2021 Jul;29(2):111-113.
3
Impact of the SARS-CoV-2 pandemic on the diagnostic delay of oral carcinoma: a retrospective analysis.SARS-CoV-2 大流行对口腔癌诊断延迟的影响:回顾性分析。
Minerva Dent Oral Sci. 2022 Dec;71(6):308-317. doi: 10.23736/S2724-6329.22.04645-9.
4
Increased Delay in Diagnosis, but Not Treatment, Among Patients With Oral Cancer During the COVID-19 Pandemic.在新冠疫情期间,口腔癌患者的诊断延迟增加,但治疗延迟未增加。
JAMA Otolaryngol Head Neck Surg. 2023 Jan 1;149(1):91-92. doi: 10.1001/jamaoto.2022.3652.
5
Impact of COVID-19 pandemic on lung cancer treatment scheduling.COVID-19 大流行对肺癌治疗计划的影响。
Thorac Cancer. 2020 Oct;11(10):2983-2986. doi: 10.1111/1759-7714.13615. Epub 2020 Aug 12.
6
The effect of the COVID-19 pandemic on the diagnosis and progression of oral cancer.2019年冠状病毒病疫情对口腔癌诊断及病情进展的影响。
Int J Oral Maxillofac Surg. 2024 Aug;53(8):629-634. doi: 10.1016/j.ijom.2024.02.003. Epub 2024 Feb 22.
7
THE IMPACT OF COVID-19 ON HEAD AND NECK CANCER TREATMENT DELAY.COVID-19 对头颈部癌症治疗延误的影响。
Acta Clin Croat. 2022 Oct;61(Suppl 4):19-25. doi: 10.20471/acc.2022.61.s4.2.
8
Covid-19 pandemic: A new contributing factor to diagnostic and treatment delay in oral cancer patients.新冠疫情:口腔癌患者诊断和治疗延迟的一个新促成因素。
Oral Oncol. 2021 May;116:105176. doi: 10.1016/j.oraloncology.2020.105176. Epub 2021 Jan 15.
9
Effects of COVID-19 Lockdown on Tumour Burden of Melanoma and Cutaneous Squamous Cell Carcinoma.新冠疫情封锁对黑素瘤和皮肤鳞状细胞癌肿瘤负担的影响。
Acta Derm Venereol. 2021 Aug 25;101(8):adv00525. doi: 10.2340/00015555-3890.
10
Delays in Stroke Onset to Hospital Arrival Time During COVID-19.新冠疫情期间脑卒中发病到医院就诊时间的延迟。
Stroke. 2020 Jul;51(7):2228-2231. doi: 10.1161/STROKEAHA.120.030105. Epub 2020 May 20.

引用本文的文献

1
Shorter Time to Biopsy of Patients with Head and Neck Squamous Cell Carcinoma During the COVID-19 Pandemic in Hungary.匈牙利新冠疫情期间头颈部鳞状细胞癌患者活检时间缩短
Cancers (Basel). 2025 Jan 23;17(3):360. doi: 10.3390/cancers17030360.
2
The impact of the COVID-19 pandemic on time to treatment in head and neck cancer management: a systematic review.2019年冠状病毒病大流行对头颈癌治疗及时性的影响:一项系统评价
Acta Oncol. 2025 Jan 28;64:156-166. doi: 10.2340/1651-226X.2025.41366.
3
[Impact of the coronavirus pandemic on the diagnosis and treatment of head and neck cancer].

本文引用的文献

1
Delayed presentation of head and neck cancer patients during COVID-19 pandemic.COVID-19 大流行期间头颈部癌症患者就诊延迟。
Eur Arch Otorhinolaryngol. 2021 Dec;278(12):5081-5085. doi: 10.1007/s00405-021-06728-2. Epub 2021 Mar 6.
2
Treatment delay in early-stage oral squamous cell carcinoma and its relation to survival.早期口腔鳞状细胞癌的治疗延误及其与生存的关系。
J Craniomaxillofac Surg. 2021 Jun;49(6):462-467. doi: 10.1016/j.jcms.2021.02.007. Epub 2021 Feb 12.
3
Time to Surgery and Survival in Head and Neck Cancer.
[冠状病毒大流行对头颈癌诊断和治疗的影响]
HNO. 2024 Dec;72(12):893-899. doi: 10.1007/s00106-024-01520-0. Epub 2024 Nov 6.
4
Negative excess oral and pharyngeal cancer mortality in Europe during the early pandemic years.疫情早期欧洲口腔和咽癌超额死亡率为负。
Oral Dis. 2025 Jan;31(1):121-128. doi: 10.1111/odi.15055. Epub 2024 Jun 27.
5
Exploring Prevalence Trends of Jaw Bone Pathologies: A Three-Year Institutional Study.探索颌骨病变的患病率趋势:一项为期三年的机构研究。
Cureus. 2024 May 18;16(5):e60574. doi: 10.7759/cureus.60574. eCollection 2024 May.
6
Increasing stage and depth of invasion (DOI) in patients with tongue cancer during the COVID-19 pandemic: A time series study.2019年冠状病毒病大流行期间舌癌患者侵袭分期和深度增加的时间序列研究
Health Sci Rep. 2024 Jan 22;7(1):e1832. doi: 10.1002/hsr2.1832. eCollection 2024 Jan.
7
[Impact of the COVID-19 pandemic on the diagnosis and treatment of patients with head and neck cancer in Brandenburg and Berlin].[新冠疫情对勃兰登堡州和柏林市头颈癌患者诊断与治疗的影响]
HNO. 2024 Feb;72(2):90-101. doi: 10.1007/s00106-023-01396-6. Epub 2023 Dec 20.
8
Primary Diagnoses of Squamous Cell Carcinoma of the Head and Neck During the COVID-19 Pandemic.COVID-19大流行期间头颈部鳞状细胞癌的主要诊断
Dtsch Arztebl Int. 2023 Oct 20;120(42):719-720. doi: 10.3238/arztebl.m2023.0177.
9
COVID-19 impact on the management of head and neck cancer: a French single-centre experience.COVID-19 对头颈部癌症治疗的影响:法国单中心经验。
Eur Arch Otorhinolaryngol. 2024 Feb;281(2):873-882. doi: 10.1007/s00405-023-08245-w. Epub 2023 Oct 16.
10
Stage shift and relative survival for head and neck cancer during the 2020 COVID-19 pandemic: a population-based study of temporal trends.2020年新冠疫情期间头颈癌的分期变化及相对生存率:一项基于人群的时间趋势研究
Front Oncol. 2023 Sep 20;13:1253968. doi: 10.3389/fonc.2023.1253968. eCollection 2023.
头颈部癌症的手术时间与生存。
Ann Surg Oncol. 2021 Feb;28(2):877-885. doi: 10.1245/s10434-020-09326-4. Epub 2020 Nov 13.
4
Integrated Survival Estimates for Cancer Treatment Delay Among Adults With Cancer During the COVID-19 Pandemic.癌症患者在 COVID-19 大流行期间治疗延误的综合生存估计。
JAMA Oncol. 2020 Dec 1;6(12):1881-1889. doi: 10.1001/jamaoncol.2020.5403.
5
Impact of COVID-19 pandemic on lung cancer treatment scheduling.COVID-19 大流行对肺癌治疗计划的影响。
Thorac Cancer. 2020 Oct;11(10):2983-2986. doi: 10.1111/1759-7714.13615. Epub 2020 Aug 12.
6
Nonsurgical management of resectable oral cavity cancer in the wake of COVID-19: A rapid review and meta-analysis.新冠疫情背景下可切除口腔癌的非手术治疗:快速综述和荟萃分析。
Oral Oncol. 2020 Oct;109:104849. doi: 10.1016/j.oraloncology.2020.104849. Epub 2020 Jun 10.
7
Effect of COVID-19 Epidemic on Delay of Diagnosis and Treatment Path for Patients with Nasopharyngeal Carcinoma.新型冠状病毒肺炎疫情对鼻咽癌患者诊断及治疗路径延误的影响
Cancer Manag Res. 2020 May 25;12:3859-3864. doi: 10.2147/CMAR.S254093. eCollection 2020.
8
COVID-19 in patients with thoracic malignancies (TERAVOLT): first results of an international, registry-based, cohort study.胸恶性肿瘤患者的 COVID-19(TERAVOLT):一项国际、基于登记的队列研究的初步结果。
Lancet Oncol. 2020 Jul;21(7):914-922. doi: 10.1016/S1470-2045(20)30314-4. Epub 2020 Jun 12.
9
Clinical characteristics and risk factors associated with COVID-19 disease severity in patients with cancer in Wuhan, China: a multicentre, retrospective, cohort study.中国武汉癌症患者 COVID-19 疾病严重程度相关的临床特征和危险因素:一项多中心、回顾性、队列研究。
Lancet Oncol. 2020 Jul;21(7):893-903. doi: 10.1016/S1470-2045(20)30309-0. Epub 2020 May 29.
10
Changes in head and neck oncologic practice during the COVID-19 pandemic.COVID-19 大流行期间头颈部肿瘤诊治的变化。
Head Neck. 2020 Jul;42(7):1448-1453. doi: 10.1002/hed.26233. Epub 2020 Jun 11.