口腔癌患者在 COVID-19 大流行的第一年中的治疗延误和肿瘤大小。
Treatment delay and tumor size in patients with oral cancer during the first year of the COVID-19 pandemic.
机构信息
Department of Oral and Cranio-Maxillofacial Surgery, Heidelberg University Hospital, Heidelberg, Germany.
Institute of Medical Biometry and Informatics, Heidelberg University Hospital, Heidelberg, Germany.
出版信息
Head Neck. 2021 Nov;43(11):3493-3497. doi: 10.1002/hed.26858. Epub 2021 Sep 8.
BACKGROUND
We set out to investigate how the ongoing coronavirus pandemic affected the size of tumors and the duration of treatment delay in patients with surgically treated oral squamous cell carcinoma.
METHODS
Patients with surgically treated oral cavity squamous cell carcinoma were assessed retrospectively and divided into two groups depending on when they had first presented at our clinic. Patients presenting from 2010 to 2019, that is, before COVID-19 onset (n = 566) were compared to patients presenting in 2020 (n = 58).
RESULTS
A total of 624 patients were included. Treatment delay was significantly longer in 2020 (median = 45 days) versus 2010-2019 (median = 35 days) (p = 0.004). We observed a higher pathological T classification in 2020 (p = 0.046), whereas pathological N classification was unchanged between groups (p = 0.843).
CONCLUSIONS
While extraordinary efforts continue to be made in the context of the pandemic, it is imperative that this does not lead to significant disadvantages for many people with oral cancer.
背景
我们旨在调查正在进行的冠状病毒大流行如何影响接受手术治疗的口腔鳞状细胞癌患者肿瘤大小和治疗延迟时间。
方法
回顾性评估接受手术治疗的口腔腔鳞状细胞癌患者，并根据他们首次就诊于我们诊所的时间将其分为两组。将 2010 年至 2019 年（即 COVID-19 发病前）就诊的患者（n=566）与 2020 年就诊的患者（n=58）进行比较。
结果
共纳入 624 例患者。2020 年的治疗延迟时间明显更长（中位数=45 天），而 2010-2019 年的治疗延迟时间（中位数=35 天）更短（p=0.004）。我们发现 2020 年的病理 T 分类更高（p=0.046），而两组之间的病理 N 分类没有变化（p=0.843）。
结论
虽然在大流行背景下继续做出非凡努力，但至关重要的是，这不会给许多口腔癌患者带来重大不利影响。
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