Chen Hui, Zhou Jing, Huang Qian, Si Ming-Yu, Su Xiao-You, Li Jing
Department of Epidemiology and Health Statistics,Chengdu 610041,China.
Department of Student Affairs,West China School of Public Health and West China Fourth Hospital,Sichuan University,Chengdu 610041,China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2021 Aug;43(4):545-550. doi: 10.3881/j.issn.1000-503X.13153.
Objective To investigate the knowledge about human papillomavirus(HPV)and its vaccines,HPV vaccination status,and vaccination willingness among the freshmen majoring in liberal arts,sciences,and medicine in western China,so as to provide evidence-based suggestions for health education among university students and to increase their vaccination. Methods By convenience sampling,stratified sampling,and cluster sampling,an online questionnaire survey was conducted among freshmen in a comprehensive university in Chengdu.The differences among the groups were compared by test,and non-conditional logistic regression was performed to analyze the influencing factors of willingness to vaccination. Results A total of 881 participants were included in this study,including 419 males and 462 females.The vaccination rate of females was 3.5%(16/462).Of all the university students,59.1%,67.5%,and 56.3% had heard of HPV,HPV-related diseases,and HPV vaccines,respectively,and only 10.4%,10.6%,and 27.8% knew "HPV infection usually does not cause symptoms","HPV infection is usually transient and mostly spontaneous regressive",and "HPV infection is very common".Females and medical students had more related knowledge than males and non-medical students(=0.035,=0.021).Of all the university students,65.7% were willing to be vaccinated against HPV.The high cost of vaccination(50.8%),worry about the side effects adverse reaction(46.3%),and lack of sexual life(43.4%)were the main reasons for the reluctance to be vaccinated.Gender,education background of parents,history of self-financed vaccination,attitude towards premarital sexual behavior,history of sexual behavior,and knowledge of HPV were the influencing factors of vaccination willingness. Conclusions The freshmen had a low rate of HPV vaccination and limited detailed knowledge about HPV and its vaccines.Health education campaign is urgently called for among university students regarding HPV infection as well as the safety,effectiveness,and side effects of HPV vaccines.More attention should be paid to the health education of male and non-medical students.
目的 调查中国西部文科、理科及医学专业大一新生对人乳头瘤病毒（HPV）及其疫苗的认知情况、HPV疫苗接种现状及接种意愿，为大学生健康教育及提高其疫苗接种率提供循证建议。方法 通过便利抽样、分层抽样和整群抽样的方法，对成都某综合性大学的大一新生进行在线问卷调查。采用检验比较组间差异，并进行非条件logistic回归分析接种意愿的影响因素。结果 本研究共纳入881名参与者，其中男性419名，女性462名。女性接种率为3.5%（16/462）。在所有大学生中，分别有59.1%、67.5%和56.3%听说过HPV、HPV相关疾病和HPV疫苗，只有10.4%、10.6%和27.8%知道“HPV感染通常无明显症状”“HPV感染通常是短暂的，大多可自然消退”以及“HPV感染非常普遍”。女性和医学专业学生比男性和非医学专业学生有更多的相关知识（=0.035，=0.021）。在所有大学生中，65.7%愿意接种HPV疫苗。接种费用高（50.8%）、担心副作用不良反应（46.3%）和没有性生活（43.4%）是不愿意接种的主要原因。性别、父母教育背景、自费疫苗接种史、对婚前性行为的态度、性行为史和HPV知识是接种意愿的影响因素。结论 大一新生HPV疫苗接种率较低，对HPV及其疫苗的详细了解有限。急需在大学生中开展关于HPV感染以及HPV疫苗安全性、有效性和副作用的健康教育。应更加关注男性和非医学专业学生的健康教育。
