Department of General Medicine, Government Medical College and Hospital, Sector 32, Chandigarh, India.
Department of Pathology, Government Medical College and Hospital, Sector 32, Chandigarh, India.
Int J Mycobacteriol. 2021 Jul-Sep;10(3):330-334. doi: 10.4103/ijmy.ijmy_25_21.
Tuberculosis (TB) and leprosy are two chronic mycobacterial infections caused by intracellular Gram-positive aerobic acid-fast bacilli. Both have highly variable presentations depending on immunological milieu of the host and account for significant disease morbidity. The burden of these age-old infections of humanity still remains high in India. Regardless of the same geographical endemicity of the two, coinfections are sparsely reported. Indeed, studies have revealed an antagonism between them. Of the few coinfections reported in the past, majority were diagnosed over a temporal sequence, with one occurring after the other, and most of these were localized forms of TB associated with leprosy. Only a single case of disseminated TB and lepromatous leprosy has been reported in the medical literature till date. Here, we report another rare case of disseminated TB and lepromatous leprosy that ultimately proved fatal for the patient. The diagnosis of the two diseases was made simultaneously which is again infrequent in the reported literature.
结核病（TB）和麻风病是两种由细胞内革兰氏阳性需氧抗酸杆菌引起的慢性分枝杆菌感染。这两种疾病的表现高度可变，取决于宿主的免疫环境，导致了严重的疾病发病率。这两种古老的人类传染病在印度的负担仍然很高。尽管这两种疾病在同一地理区域流行，但合并感染的报道很少。事实上，研究表明它们之间存在拮抗作用。过去报道的少数合并感染中，大多数是按时间顺序诊断的，一种在另一种之后发生，其中大多数是与麻风病相关的局部形式的结核病。迄今为止，在医学文献中仅报告了一例播散性结核病和瘤型麻风病的病例。在这里，我们报告了另一个罕见的播散性结核病和瘤型麻风病的病例，最终导致患者死亡。这两种疾病的诊断是同时进行的，这在已报道的文献中也很少见。
