Werntz D A, Bickford R G, Shannahoff-Khalsa D
Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla 92093.
Hum Neurobiol. 1987;6(3):165-71.
We have previously demonstrated by the integration of EEG amplitudes, that an ultradian rhythm of alternating cerebral dominance exists in humans. This rhythm is tightly coupled with the nasal cycle, since its lateralization correlates with shifts in airflow through the left and right nostrils, where relatively greater integrated amplitudes in one hemisphere correspond to predominant airflow in the contralateral nostril. The nasal cycle is known to be regulated by the sympathetic and parasympathetic branches of the autonomic nervous system. This dynamic lateralization of alternating activity in the autonomic nervous system exists in other peripheral structures and is also likely to be the mode of regulation of the cortical rhythm. This paper shows that forced nostril breathing in one nostril produces a relative increase in the EEG amplitude in the contralateral hemisphere. This phenomena was demonstrated in 5 out of 5 untrained subjects. These results suggest the possibility of a non-invasive approach in the treatment of states of psychopathology where lateralized cerebral dysfunction have been shown to occur.
我们之前通过整合脑电图振幅证明，人类存在交替性大脑优势的超日节律。这种节律与鼻周期紧密相关，因为其偏侧化与通过左右鼻孔的气流变化相关，其中一个半球相对较大的整合振幅对应对侧鼻孔的主要气流。已知鼻周期受自主神经系统的交感和副交感分支调节。自主神经系统中交替活动的这种动态偏侧化存在于其他外周结构中，也可能是皮质节律的调节方式。本文表明，单侧鼻孔强制呼吸会使对侧半球的脑电图振幅相对增加。这一现象在5名未经训练的受试者中均得到证实。这些结果提示了一种非侵入性方法用于治疗已显示存在大脑功能偏侧化障碍的精神病理状态的可能性。
