Gulhane Training and Research Hospital, Department of Urology - Ankara, Turkey.
Gulhane Training and Research Hospital, In Vitro Fertilization Center - Ankara, Turkey.
Rev Assoc Med Bras (1992). 2021 Apr;67(4):577-584. doi: 10.1590/1806-9282.20201096.
Testicular tumor constitutes 1% of male neoplasms. Infertility can be determined in patients with testicular tumors before orchiectomy due to the deterioration of spermatogenesis. The aim of this study was to show the clinical, radiological, and pathological characteristics and spermiogram results of patients with testicular tumor and their relationship with each other.
The data of patients who underwent orchiectomy due to testicular tumor between 2016 and 2019 were reviewed retrospectively. These data included sociodemographic data of the patients, pretreatment spermiogram characteristics, level of serum tumor markers, characteristics of the ultrasonography, type of orchiectomy, and histopathological examination.
This study included 53 male patients, with a mean age of 33.51±12.86 years. The mean levels of all tumor markers were above the reference levels. The mean tumor size was 34.68±23.32 mm. Multiple localizations and microlithiasis were detected in 11.3 and 13.2% of the tumors, respectively. The most common masses were hypoechoic (n=37; 69.8%) and hypervascular (n=47; 81%). Spermiogram and cryopreservation were performed in 29 (54.7%) of 53 patients preoperatively. The mean sperm concentration before orchiectomy was 24.21×106 /mL and group A sperm motility 0.79%, group B sperm motility 39.10%, group C sperm motility 9.83%, and group D sperm motility 22.69% in testicular tumors.
Spermatogenesis adversely affected before the treatment due to local and systemic effects of testicular cancer. Fertility expectations can be increased in the subsequent years by semen analysis and referral to cryopreservation.
睾丸肿瘤占男性肿瘤的 1%。由于精子发生恶化，睾丸肿瘤患者在睾丸切除术之前可能会出现不育。本研究旨在展示睾丸肿瘤患者的临床、放射学和病理学特征及其与彼此的关系，并展示精子分析结果。
回顾性分析 2016 年至 2019 年因睾丸肿瘤行睾丸切除术的患者资料。这些数据包括患者的社会人口统计学资料、治疗前精子分析特征、血清肿瘤标志物水平、超声特征、睾丸切除术类型和组织病理学检查。
本研究纳入 53 例男性患者，平均年龄为 33.51±12.86 岁。所有肿瘤标志物的平均水平均高于参考水平。平均肿瘤大小为 34.68±23.32mm。11.3%和 13.2%的肿瘤分别检测到多个定位和微结石。最常见的肿块是低回声（n=37；69.8%）和高血管（n=47；81%）。53 例患者中有 29 例（54.7%）在术前进行了精子分析和冷冻保存。睾丸肿瘤患者在睾丸切除术前的平均精子浓度为 24.21×106 /mL，A 级精子活力为 0.79%，B 级精子活力为 39.10%，C 级精子活力为 9.83%，D 级精子活力为 22.69%。
由于睾丸癌的局部和全身影响，治疗前精子发生受到不利影响。通过精液分析和转介冷冻保存，可以在随后的几年中增加生育期望。
