Department of Medical Biotechnology and Translational Medicine, University of Milano, Segrate, Milano, Italy.
Adv Exp Med Biol. 2021;1325:61-102. doi: 10.1007/978-3-030-70115-4_3.
Glycosphingolipids are amphiphilic plasma membrane components formed by a glycan linked to a specific lipid moiety. In this chapter we report on these compounds, on their role played in our cells to maintain the correct cell biology.In detail, we report on their structure, on their metabolic processes, on their interaction with proteins and from this, their property to modulate positively in health and negatively in disease, the cell signaling and cell biology.
糖脂是由糖连接到特定脂质部分形成的两亲性质膜成分。在本章中,我们报告了这些化合物,以及它们在我们的细胞中维持正确的细胞生物学功能所起的作用。详细地说,我们报告了它们的结构、代谢过程、与蛋白质的相互作用,以及由此产生的它们在健康和疾病中正向调节细胞信号转导和细胞生物学的特性。