Department of Otorhinolaryngology - Head and Neck Surgery, Istanbul Faculty of Medicine, Istanbul UniversityIstanbul, Turkey.
Fulya Imaging Center, Istanbul, Turkey.
J Laryngol Otol. 2021 Nov;135(11):1010-1018. doi: 10.1017/S0022215121002425. Epub 2021 Sep 9.
The primary goal of this study was to evaluate the association between olfactory dysfunction or taste impairment and disease severity and radiological findings in coronavirus disease-2019. The secondary goal was to assess the prevalence, severity and course of olfactory dysfunction or taste impairment in patients with coronavirus disease 2019.
This prospective observational cohort study evaluated patients hospitalised with coronavirus disease 2019 between April 1 and 1 May 2020. Olfactory dysfunction and taste impairment were evaluated by two questionnaires. Chest computed tomography findings and coronavirus disease-2019 severity were assessed.
Among 133 patients, 23.3 per cent and 30.8 per cent experienced olfactory dysfunction and taste impairment, respectively, and 17.2 per cent experienced both. The mean age was 56.03 years, and 64.7 per cent were male and 35.3 per cent were female. No statistically significant association was found between olfactory dysfunction (p = 0.706) and taste impairment (p = 0.35) with either disease severity or chest computed tomography grading.
Olfactory dysfunction or taste impairment does not have prognostic importance in patients with coronavirus disease 2019.
本研究的主要目的是评估嗅觉功能障碍或味觉障碍与 2019 冠状病毒病严重程度和影像学表现之间的关系。次要目的是评估 2019 冠状病毒病患者嗅觉功能障碍或味觉障碍的患病率、严重程度和病程。
这是一项前瞻性观察性队列研究，评估了 2020 年 4 月 1 日至 5 月 1 日期间因 2019 冠状病毒病住院的患者。通过两份问卷评估嗅觉功能障碍和味觉障碍。评估胸部计算机断层扫描结果和 2019 冠状病毒病严重程度。
在 133 名患者中，分别有 23.3%和 30.8%的患者出现嗅觉功能障碍和味觉障碍，17.2%的患者同时出现两种障碍。患者的平均年龄为 56.03 岁，64.7%为男性，35.3%为女性。嗅觉功能障碍（p = 0.706）和味觉障碍（p = 0.35）与疾病严重程度或胸部计算机断层扫描分级均无统计学显著相关性。
嗅觉功能障碍或味觉障碍在 2019 冠状病毒病患者中无预后意义。
