Obstetrics and gynaecology, Seirei Hamamatsu Hospital, Hamamatsu, Shizuoka, Japan
Obstetrics and gynaecology, Seirei Hamamatsu Hospital, Hamamatsu, Shizuoka, Japan.
BMJ Case Rep. 2021 Sep 8;14(9):e244664. doi: 10.1136/bcr-2021-244664.
A 35-year-old woman (gravida 1, para 0) underwent termination of pregnancy (ToP) at 12 weeks of gestation. One month after ToP, she experienced significant vaginal bleeding and the mass with blood flow was identified on imaging. The presence of a placental polyp with arteriovenous malformation (AVM) was suspected on transvaginal sonography and MRI. Since the bleeding had ceased when she visited our hospital, we decided to treat the placental polyp with AVM with gonadotropin-releasing hormone (GnRH) antagonist therapy instead of surgery. Two months after GnRH antagonist treatment, the mass and blood flow in the uterus disappeared. Menstruation resumed 1 month after the completion of treatment. In our case, we were able to successfully treat placental polyps with AVM using GnRH antagonist therapy.
一位 35 岁女性（孕 1 产 0）于妊娠 12 周时行人工流产术。人流术后 1 个月，患者出现阴道大量流血，影像学检查提示宫腔内血流丰富的占位。经阴道超声和 MRI 检查提示胎盘息肉伴动静脉畸形（arteriovenous malformation，AVM）。因患者就诊时阴道流血已停止，我们决定采用促性腺激素释放激素（gonadotropin-releasing hormone，GnRH）拮抗剂治疗胎盘息肉伴 AVM，而非手术治疗。GnRH 拮抗剂治疗 2 个月后，子宫内占位及血流信号消失。治疗结束 1 个月后患者恢复月经。本例患者成功采用 GnRH 拮抗剂治疗胎盘息肉伴 AVM。
