Past President of the International Menopause Society and Consultant, Department of Gynecology, Stellenbosch University and Mediclinic Panorama, Cape Town, South Africa.
President of the International Menopause Society and Professor of Obstetrics and Gynecology, New York University, Grossman School of Medicine, New York, USA.
Climacteric. 2021 Oct;24(5):498-504. doi: 10.1080/13697137.2021.1950967.
Osteoporosis and associated fractures present a major challenge in improving global health outcomes. Key clinical aspects are the definition of osteoporosis and associated fractures, fracture risk prediction, stratification of risk of fracture, intervention thresholds and the most appropriate intervention based on integration of aforementioned. Correct understanding and application of these concepts are essential to stem the increasing tide of fragility fractures associated with an aging population. The role of muscle strength and function, sarcopenia, and the newly emerging concept of osteosarcopenia in maintaining bone health are discussed in detail.
骨质疏松症及相关骨折严重影响全球健康，是目前面临的主要挑战。关键的临床问题包括骨质疏松症及相关骨折的定义、骨折风险预测、骨折风险分层、干预阈值以及根据上述内容选择最合适的干预措施。正确理解和应用这些概念对于遏制与人口老龄化相关的脆性骨折不断增加至关重要。本文详细讨论了肌肉力量和功能、肌肉减少症以及新出现的骨肌减少症概念在维持骨骼健康方面的作用。
