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不惜一切代价要个孩子?探讨体外受精背景下未经验证的辅助治疗的使用与提供情况。

A Baby at All Costs? Exploring the Use and Provision of Unproven Adjuvant Treatments in the Context of IVF.

作者信息

Jones Georgina L, Lang Victoria, Hudson Nicky

机构信息

Department of Psychology, School of Social Sciences, Leeds Beckett University, Leeds, United Kingdom.

Centre for Reproduction Research, De Montfort University, Leicester, United Kingdom.

出版信息

Semin Reprod Med. 2021 Nov;39(5-06):220-226. doi: 10.1055/s-0041-1731789. Epub 2021 Sep 9.

DOI:10.1055/s-0041-1731789
PMID:34500475
Abstract

The year 2018 marked 40 years since the birth of Louise Brown, the first baby born as a result of pioneering in vitro fertilization (IVF) treatment. Since then, advances have seen a wide range of reproductive technologies emerge into clinical practice, including adjuvant treatments often referred to as IVF "add-ons." However, these "optional extras" have faced growing criticism, especially when they have often come at additional financial cost to the patient and have little evidence supporting their efficacy to improve pregnancy or birth rates. Despite this, according to the latest national patient survey by the Human Fertilisation and Embryology Authority, three quarters of patients who had fertility treatment in the United Kingdom in the past two years had at least one type of treatment add-on highlighting the growing demand for these interventions. This article uses a psychosocial perspective to consider the motivations behind patient and clinician behavior along with the wider societal and economic factors that may be impacting upon the increase in the use of adjuvant treatments in fertility clinics more widely. It suggests the reasons fertility patients use unproven "optional extras" are complex, with interpersonal, psychological, and social factors intertwining to generate an increase in the use of IVF add-ons.

摘要

2018年是路易丝·布朗诞生40周年,她是首例通过开创性的体外受精(IVF)治疗诞生的婴儿。从那时起,生殖技术不断进步,多种生殖技术已应用于临床实践,包括常被称为IVF“附加疗法”的辅助治疗。然而,这些“可选额外项目”面临越来越多的批评,特别是因为它们往往会给患者带来额外的经济负担,而且几乎没有证据支持它们能提高妊娠率或出生率。尽管如此,根据人类受精与胚胎学管理局最新的全国患者调查,在过去两年中,英国四分之三接受生育治疗的患者至少接受过一种附加治疗,这凸显了对这些干预措施的需求不断增加。本文从社会心理角度探讨了患者和临床医生行为背后的动机,以及可能更广泛地影响生育诊所辅助治疗使用增加的社会和经济因素。文章指出,生育患者使用未经证实的“可选额外项目”的原因很复杂,人际、心理和社会因素相互交织,导致IVF附加疗法的使用增加。

相似文献

1
A Baby at All Costs? Exploring the Use and Provision of Unproven Adjuvant Treatments in the Context of IVF.不惜一切代价要个孩子?探讨体外受精背景下未经验证的辅助治疗的使用与提供情况。
Semin Reprod Med. 2021 Nov;39(5-06):220-226. doi: 10.1055/s-0041-1731789. Epub 2021 Sep 9.
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How common is add-on use and how do patients decide whether to use them? A national survey of IVF patients.附加药物使用的情况有多常见,患者又是如何决定是否使用它们的呢?一项针对试管婴儿患者的全国性调查。
Hum Reprod. 2021 Jun 18;36(7):1854-1861. doi: 10.1093/humrep/deab098.
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The crafting of hope: Contextualising add-ons in the treatment trajectories of IVF patients.希望的构建:在 IVF 患者的治疗轨迹中对附加治疗进行情境化理解。
Soc Sci Med. 2021 Oct;287:114317. doi: 10.1016/j.socscimed.2021.114317. Epub 2021 Aug 14.
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The prevalence, promotion and pricing of three IVF add-ons on fertility clinic websites.生育诊所网站上三种试管婴儿附加服务的流行程度、推广情况和定价。
Reprod Biomed Online. 2020 Nov;41(5):801-806. doi: 10.1016/j.rbmo.2020.07.021. Epub 2020 Jul 27.
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VALUE study: a protocol for a qualitative semi-structured interview study of IVF add-ons use by patients, clinicians and embryologists in the UK and Australia.VALUE 研究:一项在英国和澳大利亚对 IVF 附加治疗的使用进行定性半结构式访谈研究的方案,研究对象包括患者、临床医生和胚胎学家。
BMJ Open. 2021 May 21;11(5):e047307. doi: 10.1136/bmjopen-2020-047307.
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The efficacy of add-ons: selected IVF "add-on" procedures and future directions.附加治疗的疗效:精选的 IVF“附加”程序和未来方向。
J Assist Reprod Genet. 2022 Mar;39(3):581-589. doi: 10.1007/s10815-022-02410-6. Epub 2022 Jan 23.
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Applying a simplified economic evaluation approach to evaluate infertility treatments in clinical practice.应用简化的经济评价方法评估临床实践中的不孕治疗。
Hum Reprod. 2024 Mar 1;39(3):448-453. doi: 10.1093/humrep/dead265.
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Is it ethical to provide IVF add-ons when there is no evidence of a benefit if the patient requests it?如果患者提出要求,而没有证据表明其有益,那么提供 IVF 附加服务是否符合伦理?
J Med Ethics. 2019 May;45(5):346-350. doi: 10.1136/medethics-2018-104983. Epub 2019 Feb 11.
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In vitro fertilization and multiple pregnancies: an evidence-based analysis.体外受精与多胎妊娠:一项基于证据的分析。
Ont Health Technol Assess Ser. 2006;6(18):1-63. Epub 2006 Oct 1.
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Is the use of IVF add-on treatments driven by patients or clinics? Findings from a UK patient survey.体外受精附加治疗的使用是由患者还是诊所推动的?英国一项患者调查的结果。
Hum Fertil (Camb). 2023 Dec;26(2):365-372. doi: 10.1080/14647273.2023.2197628. Epub 2023 Apr 16.

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