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内耳神经鞘瘤患者人工耳蜗植入的挑战:手术方法与听觉结果

Challenges of Cochlear Implantation in Intralabyrinthine Schwannoma Patients: Surgical Procedures and Auditory Outcome.

作者信息

Häussler Sophia Marie, Szczepek Agnieszka J, Gräbel Stefan, Olze Heidi

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany.

Department of Otorhinolaryngology, Head and Neck Surgery, Campus Charité Mitte, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany.

出版信息

J Clin Med. 2021 Aug 30;10(17):3899. doi: 10.3390/jcm10173899.

Abstract

Intralabyrinthine schwannoma (ILS) is a rare benign tumor of the inner ear potentially causing unilateral sensorineural hearing loss and vertigo. This study evaluated the outcome of one surgical session comprising microsurgical ILS resection and cochlear implantation in terms of surgical feasibility, complications, and auditory outcome. Ten clinically and histologically confirmed ILS patients included in this study (three women and seven men; mean age 56.4 ± 8.6) underwent surgery between July 2015 and February 2020. Eight patients had intracochlear tumor location; the remaining two had vestibulocochlear and intravestibular ILS. One of the three following methods was used for tumor removal: an extended cochleostomy, subtotal cochleoectomy, or a translabyrinthine approach. Although negligible improvement was observed in two of the patients, two patients were lost to follow-up, and one opted out from using CI, the speech perception of the five remaining ILS patients improved as per the Freiburg Monosyllable Test (FMT) from 0% before surgery to 45- 50% after the implantation. Our study supports the presented surgical approach's feasibility and safety, enabling tumor removal and hearing restoration shortly after surgery.

摘要

迷路内神经鞘瘤(ILS)是一种罕见的内耳良性肿瘤,可能导致单侧感音神经性听力损失和眩晕。本研究从手术可行性、并发症和听觉结果方面评估了包括显微手术切除ILS和人工耳蜗植入的单次手术的结果。本研究纳入的10例经临床和组织学确诊的ILS患者(3名女性和7名男性;平均年龄56.4±8.6岁)于2015年7月至2020年2月接受了手术。8例患者的肿瘤位于耳蜗内;其余2例为前庭蜗神经和迷路内ILS。采用以下三种方法之一进行肿瘤切除:扩大耳蜗造口术、次全耳蜗切除术或经迷路入路。尽管有2例患者的改善微不足道,2例患者失访,1例选择不使用人工耳蜗,但根据弗莱堡单音节测试(FMT),其余5例ILS患者的言语感知能力从术前的0%提高到植入后的45%-50%。我们的研究支持了所提出的手术方法的可行性和安全性,能够在手术后不久切除肿瘤并恢复听力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8589/8432191/f6c19c9571c8/jcm-10-03899-g002.jpg

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