Department of Cardiac Vascular Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, People's Republic of China.
Department of Cardiovascular Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
Br J Nutr. 2022 May 28;127(10):1543-1548. doi: 10.1017/S0007114521003500. Epub 2021 Sep 10.
The prevalence of malnutrition is high among oncology patients in Northern China. Malnutrition is related to the longer hospital stay, and it can be used to predict the prognostic outcome of patients. This work focused on investigating the relationship of nutritional condition with the length of hospital stay (LOS) in Northern Chinese patients with lung adenocarcinoma (LUAD). The Patient-Generated Subjective Global Assessment (PG-SGA), Nutritional Risk Screening 2002 (NRS 2002) score, recent weight loss and BMI were assessed in a probabilistic sample of 389 LUAD patients without epidermal growth factor receptor (EGFR) mutations. This study collected the demographic and clinical features of patients in a prospective manner. Then, we examined the association of nutritional status with LOS among the population developing LUAD. According to the PG-SGA, 63 (16·3 %), 174 (44·7 %) and 78 (20·1 %) patients were at risk for undernutrition, moderate undernutrition and severe undernutrition, respectively. Nutritional risk was found in 141 (36·2 %) patients based on the NRS 2002. The average LOS for tumour patients in Northern China was 12·5 d. At admission, a risk of undernutrition or undernutrition according to the PG-SGA (P < 0·001), NRS 2002 (P < 0·001) and latest weight loss (P < 0·001) predicted the longer LOS. LOS was related to nutritional status and hospitalisation expenses (P < 0·001). LUAD patients who stayed in the ICU had a poorer nutritional status and a longer LOS (P < 0·001). In Northern Chinese patients with LUAD, a risk for undernutrition evaluated by the PG-SGA, the NRS 2002 and recent weight loss, but not BMI, could predict a longer LOS.
在中国北方，肿瘤患者的营养不良发生率很高。营养不良与住院时间延长有关，可用于预测患者的预后结局。本研究专注于调查中国北方肺腺癌（LUAD）患者的营养状况与住院时间（LOS）的关系。对无表皮生长因子受体（EGFR）突变的 389 例 LUAD 患者进行概率抽样，评估患者生成的主观整体评估（PG-SGA）、营养风险筛查 2002 评分（NRS 2002）、近期体重减轻和 BMI。本研究前瞻性地收集了患者的人口统计学和临床特征。然后，我们检查了人群中营养状况与 LOS 之间的关系。根据 PG-SGA，分别有 63（16·3%）、174（44·7%）和 78（20·1%）例患者有营养不足、中度营养不足和严重营养不足的风险。根据 NRS 2002，141（36·2%）例患者存在营养风险。中国北方肿瘤患者的平均 LOS 为 12.5 天。入院时，PG-SGA（P<0·001）、NRS 2002（P<0·001）和最新体重减轻（P<0·001）提示存在营养不足或营养不足风险的患者 LOS 更长。LOS 与营养状况和住院费用有关（P<0·001）。入住 ICU 的 LUAD 患者营养状况较差，LOS 较长（P<0·001）。在中国北方 LUAD 患者中，PG-SGA、NRS 2002 和近期体重减轻评估的营养不足风险，但 BMI 除外，可预测 LOS 较长。
