Noireau F, Gouteux J P, Duteurtre J P
ORSTOM, Laboratoire d'Entomologie Médicale et Parasitologie, Brazzaville, Congo.
Bull Soc Pathol Exot Filiales. 1987;80(5):797-803.
A field serological study using the Testryp CATT on whole blood was performed during a mass screening of sleeping sickness in a congolese focus (3,530 patients). This test which presented a good specificity (94.8%), revealed on the other hand a low positive predictive value (26.9%). The sensitivity (68.8%) confirms the previous results obtained in Congo. Association of immunoserological tests (CATT and Indirect Immunofluorescent Antibody Test) and clinical diagnosis (examination of lymph nodes) was usefulness for specify an efficient and rapid control of the human reservoir. The improvement of the CATT diagnostic value was discussed.
在刚果某流行区对3530名患者进行昏睡病大规模筛查期间，采用Testryp CATT对全血进行了现场血清学研究。该检测具有良好的特异性（94.8%），但另一方面，其阳性预测值较低（26.9%）。敏感性（68.8%）证实了此前在刚果获得的结果。免疫血清学检测（CATT和间接免疫荧光抗体检测）与临床诊断（淋巴结检查）相结合，有助于对人类传染源进行有效且快速的控制。文中还讨论了提高CATT诊断价值的方法。
