维生素 D 缺乏症在就诊于三级医院的患者中的流行情况：一项描述性横断面研究。

Vitamin D Deficiency among Patients Visiting a Tertiary Care Hospital: A Descriptive Cross-sectional Study.

机构信息

Department of Internal Medicine, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

Department of Cardiology, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2020 Nov 22;58(231):839-842. doi: 10.31729/jnma.5645.

DOI:10.31729/jnma.5645

PMID:34506404

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7775021/

Abstract

INTRODUCTION

Vitamin D deficiency is a common condition prevalent among both developed and developing countries where it is seen mostly in females. It has been linked to various skeletal and non-skeletal diseases. This study was done to find out the prevalence of Vitamin D deficiency and clinical features of deficient patients attending the outpatient department of a tertiary care hospital.

METHODS

This descriptive cross-sectional study was done among the patients attending the outpatient department of a tertiary care hospital in Kathmandu, Nepal. The study was conducted from May 2019 to July 2019. The ethical approval was taken from the Institutional Review Committee (ref no. 310520113). Convenient sampling was done. The collected data was entered in Microsoft Excel and was analyzed in the Statistical Package for the Social Sciences (SPSS) version 26.

RESULTS

Out of 481 participants, the prevalence of vitamin D deficiency was 335 (69.6%). Severe vitamin D deficiency was seen in 78 (16.2%) and insufficient vitamin D in 77 (16%) of the patients. The mean serum vitamin D concentration by gender was 22.38±17.07 ng/ml in males and 18.89±15.25 ng/ml in females. A total of 263 (54.6%) females and 72 (14.97%) males had vitamin D deficiency. The most common symptoms found in vitamin D deficiency patients were fatigue 187(55.8%), muscle cramps 131(39.1%), generalized myalgia 125(37.31%), bone and joint pain 111(33.13%).

CONCLUSIONS

Vitamin D deficiency was prevalent especially in females and elderly people. Fatigability was present in more than half of the vitamin D deficient patients.

摘要

简介

维生素 D 缺乏是一种常见病症，在发达国家和发展中国家都普遍存在，且多见于女性。它与各种骨骼和非骨骼疾病都有关联。本研究旨在找出在一家三级保健医院的门诊部就诊的维生素 D 缺乏患者的流行情况和临床特征。

方法

这是一项在尼泊尔加德满都的一家三级保健医院的门诊部进行的描述性横断面研究。该研究于 2019 年 5 月至 2019 年 7 月进行。该研究获得了机构审查委员会的批准（批准号：310520113）。采用便利抽样法。收集的数据录入 Microsoft Excel 并在统计软件包（SPSS）版本 26 中进行分析。

结果

在 481 名参与者中，维生素 D 缺乏的患病率为 335 例（69.6%）。严重维生素 D 缺乏 78 例（16.2%），维生素 D 不足 77 例（16%）。按性别计算的血清维生素 D 平均浓度为男性 22.38±17.07ng/ml，女性 18.89±15.25ng/ml。共有 263 名女性（54.6%）和 72 名男性（14.97%）患有维生素 D 缺乏症。在维生素 D 缺乏症患者中最常见的症状是疲劳 187 例（55.8%），肌肉痉挛 131 例（39.1%），全身肌肉疼痛 125 例（37.31%），骨和关节疼痛 111 例（33.13%）。