Tiwari Sanjeeb, Gc Saroj, Shrees Vijay, Maharjan Sujata, Sherpali Aakash, Bhandari Khagendra, Oli Suman
Department of General Practice, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
Maharajgunj Medical Campus, Maharajgunj, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2024 May 31;62(274):392-396. doi: 10.31729/jnma.8612.
Vitamin D deficiency presents a notable public health concern, with reported prevalence rising in hospital and community settings. It's linked to various chronic health issues and most often remains undiagnosed in developing nations. This study aimed to determine the prevalence of hypovitaminosis D among adults attending general health check-ups at a tertiary care hospital.
This descriptive cross-sectional study was conducted among adult patients visiting for general health checkups in a tertiary care centre. The patients' data from 16 April 2023 to 24 November 2023 was retrieved from the hospital record. Serum 25(OH)D was measured by using the chemiluminescence micro particles immunoassay technique and classified as deficient, insufficient, and sufficient with values <20 ng/ml, 20-29 ng/ml, and 30-100 ng/ml, respectively. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.
Out of 357 adult patients, 291 (81.51%; 95% CI: 77.49%-85.54%) Confidence Interval) had hypovitaminosis D. Among them 124 (42.61%) were categorised as vitamin D insufficient and 167 (57.39%) as deficient. The mean age of patients was 43.25±12.99 years, with 205 (70.45%) female and 86 (29.55%) male. A total of 169 (58.08%) individuals were classified as obese. Dyslipidemia was observed in 249 (85.57%) patients, with 94 (32.30%) exhibiting hypercholesterolemia.
The prevalence of hypovitaminosis D was higher than other studies done in similar settings. This higher prevalence necessitates public awareness of vitamin D's importance, urging proactive screening and management by physicians and implementation of cost-effective guidelines by policymakers.
维生素D缺乏是一个显著的公共卫生问题，据报道，在医院和社区环境中其患病率呈上升趋势。它与各种慢性健康问题相关，在发展中国家，维生素D缺乏往往未被诊断出来。本研究旨在确定在一家三级护理医院进行一般健康检查的成年人中维生素D缺乏症的患病率。
本描述性横断面研究在一家三级护理中心对前来进行一般健康检查的成年患者中开展。从医院记录中检索了2023年4月16日至2023年11月24日期间患者的数据。采用化学发光微粒免疫分析技术测定血清25(OH)D，并分别将<20 ng/ml、20 - 29 ng/ml和30 - 100 ng/ml的值分类为缺乏、不足和充足。采用便利抽样方法。在95%置信区间计算点估计值。
在357名成年患者中，291名（81.51%；95%置信区间：77.49% - 85.54%）患有维生素D缺乏症。其中124名（42.61%）被归类为维生素D不足，167名（57.39%）为缺乏。患者的平均年龄为43.25±12.99岁，女性205名（70.45%），男性86名（29.55%）。共有169名（58.08%）个体被归类为肥胖。249名（85.57%）患者存在血脂异常，其中94名（32.30%）表现为高胆固醇血症。
维生素D缺乏症的患病率高于在类似环境中进行的其他研究。这种较高的患病率需要公众意识到维生素D的重要性，促使医生进行积极的筛查和管理，并促使政策制定者实施具有成本效益的指南。
