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Changes in the Association Between Diagnostic Testing Method, Polymerase Chain Reaction Ribotype, and Clinical Outcomes From Clostridioides difficile Infection: One Institution's Experience.艰难梭菌感染诊断检测方法、聚合酶链反应核糖型与临床结局之间关联的变化：一家机构的经验。
Clin Infect Dis. 2021 Nov 2;73(9):e2883-e2889. doi: 10.1093/cid/ciaa1395.
2
Nonsteroidal Anti-Inflammatory Drugs Impact on the Outcomes of Hospitalized Patients with Infection.非甾体抗炎药对住院感染患者预后的影响
Clin Exp Gastroenterol. 2019 Dec 10;12:449-456. doi: 10.2147/CEG.S223886. eCollection 2019.
3
Misoprostol protects mice against severe Clostridium difficile infection and promotes recovery of the gut microbiota after antibiotic perturbation.米索前列醇可保护小鼠免受严重艰难梭菌感染，并促进抗生素扰乱后肠道微生物群的恢复。
Anaerobe. 2019 Aug;58:89-94. doi: 10.1016/j.anaerobe.2019.06.006. Epub 2019 Jun 17.
4
Nonsteroidal Anti-inflammatory Drugs Alter the Microbiota and Exacerbate Colitis while Dysregulating the Inflammatory Response.非甾体抗炎药改变微生物群并加重结肠炎，同时使炎症反应失调。
mBio. 2019 Jan 8;10(1):e02282-18. doi: 10.1128/mBio.02282-18.
5
Systematic review: human gut dysbiosis induced by non-antibiotic prescription medications.系统评价：非抗生素处方药诱导的人类肠道菌群失调。
Aliment Pharmacol Ther. 2018 Feb;47(3):332-345. doi: 10.1111/apt.14451. Epub 2017 Dec 5.
6
Risk factors for infections - an overview of the evidence base and challenges in data synthesis.感染的危险因素——证据基础概述及数据综合的挑战。
J Glob Health. 2017 Jun;7(1):010417. doi: 10.7189/jogh.07.010417.
7
Association between NSAIDs and Clostridium difficile-Associated Diarrhea: A Systematic Review and Meta-Analysis.非甾体抗炎药与艰难梭菌相关性腹泻的关系：系统评价和荟萃分析。
Can J Gastroenterol Hepatol. 2016;2016:7431838. doi: 10.1155/2016/7431838. Epub 2016 Mar 8.
8
Supporting information retrieval from electronic health records: A report of University of Michigan's nine-year experience in developing and using the Electronic Medical Record Search Engine (EMERSE).支持从电子健康记录中检索信息：密歇根大学开发和使用电子病历搜索引擎（EMERSE）九年经验报告。
J Biomed Inform. 2015 Jun;55:290-300. doi: 10.1016/j.jbi.2015.05.003. Epub 2015 May 13.
9
MissForest--non-parametric missing value imputation for mixed-type data.MissForest--用于混合类型数据的非参数缺失值插补。
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10
Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies.在观察性研究中估计均值差异和比例差异时，倾向得分匹配的最佳卡尺宽度。
Pharm Stat. 2011 Mar-Apr;10(2):150-61. doi: 10.1002/pst.433.

非甾体抗炎药与艰难梭菌感染风险增加无关：一项倾向评分匹配的病例对照研究。

Non-steroidal anti-inflammatory drugs are not associated with increased risk of Clostridioides difficile infection: A propensity-score-matched case-control study.

机构信息

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

Department of Pathology, University of Michigan, Ann Arbor, MI, USA.

出版信息

Anaerobe. 2021 Dec;72:102444. doi: 10.1016/j.anaerobe.2021.102444. Epub 2021 Sep 22.

DOI:10.1016/j.anaerobe.2021.102444
PMID:34506930
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8678209/
Abstract

Prior research identified an increased risk for Clostridioides difficile infection (CDI) following exposure to certain non-steroidal anti-inflammatory drugs (NSAIDs). We conducted a retrospective case-control study to evaluate the risk for CDI associated with NSAID use. NSAID use was not associated with an increased risk of CDI.

摘要

先前的研究表明，接触某些非甾体抗炎药（NSAIDs）后，艰难梭菌感染（CDI）的风险增加。我们进行了一项回顾性病例对照研究，以评估 NSAID 使用与 CDI 相关的风险。NSAID 使用与 CDI 风险增加无关。