Mihatsch M J, Zollinger H U
Med Klin. 1978 Mar 17;73(11):389-94.
Electron microscopic investigation of renal biopsies is indispensable in cases of suspected Alport's syndrome, benign (familial) hematuria, nail patella syndrome as well as for the identification of viruses, virus-like endothelial tubular structures and crystalloid deposits in cryoglobulinemia. Additional valuable information is provided for all other glomerular nephropathies especially for exact classification of glomerulonephritis. Electron microscopy can by no means be a substitute for light microscopy or immunofluorescence, respectively. Provided that clinical-pathological cooperation is optimal, best results can be obtained by simultaneous application of all three methods.
对于疑似阿尔波特综合征、良性（家族性）血尿、指甲髌骨综合征的病例，以及用于鉴定病毒、病毒样内皮管状结构和冷球蛋白血症中的晶体沉积物，肾活检的电子显微镜检查是必不可少的。对于所有其他肾小球肾病，尤其是肾小球肾炎的精确分类，也能提供额外的有价值信息。电子显微镜检查绝不能分别替代光学显微镜检查或免疫荧光检查。如果临床病理合作达到最佳状态，同时应用这三种方法可获得最佳结果。
