Subang Jaya Medical Centre, Department of Cardiology, Malaysia.
Institut Jantung Negara, Department of Cardiology, Malaysia.
Med J Malaysia. 2021 Sep;76(5):777-780.
Hypertension is a significant cardiovascular risk factor. Although the mainstay of treatment remains medication, there are a number of patients with resistant hypertension who have elevated blood pressure despite multiple medications. Failure to achieve adequately controlled blood pressures despite medications put these patients at risk of target organ damage and significant morbidity from hypertension. The renal denervation procedure involves the application of radiofrequency energy or ultrasound at the renal arteries to modulate afferent and efferent sympathetic renal activity. This treatment potentially can improve blood pressure control in patients who have resistant hypertension despite medication. This article presents two case reports of successful treatment of resistant hypertension using radiofrequency renal sympathetic denervation (RDN) at a private medical centre using the latest Spyral catheter. We also reviewed the latest RDN trials to give some insights into this procedure.
高血压是一个重要的心血管危险因素。尽管药物治疗仍然是主要的治疗方法，但仍有许多抗药性高血压患者尽管使用了多种药物，但血压仍升高。尽管使用了药物，但血压仍未得到充分控制，这些患者有靶器官损伤和高血压相关严重发病率的风险。肾脏去神经术包括在肾动脉应用射频能量或超声来调节传入和传出的肾交感神经活性。这种治疗方法可能会改善抗药性高血压患者尽管使用药物治疗但血压控制不佳的情况。本文介绍了在一家私人医疗中心使用最新的 Spyral 导管进行射频肾交感神经去神经术（RDN）成功治疗抗药性高血压的两例病例报告。我们还回顾了最新的 RDN 试验，以深入了解该程序。
