高龄妊娠在三级保健中心：一项描述性的横断面研究。

Advance Age Pregnancy in a Tertiary Care Centre: A Descriptive Cross-sectional Study.

机构信息

Department of Obstetrics and Gynaecology, Manipal College of Medical Sciences, Pokhara, Nepal.

Nobel College, Sinamangal, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2021 Apr 30;59(236):380-383. doi: 10.31729/jnma.6008.

DOI:10.31729/jnma.6008

PMID:34508532

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8369581/

Abstract

INTRODUCTION

Women who conceive at advance age are at risk of pregnancy complications and adverse foetal outcome. This study aims to find out the prevalence of pregnancy at advance age in a teaching hospital.

METHODS

A descriptive cross-sectional study was conducted between October 2019 to August 2020 at department of obstetrics and gynaecology of a tertiary care centre of Nepal, after obtaining ethical clearance from Institutional Review Committee (dated 03/09/2019 with ref no. 266) and informed consent from patient. Convenience sampling was done. All the patient who were ≥35 years and >28 weeks of gestation without any chronic illness were selected. Data and descriptive analysis were done using Statistical Package for the Social Sciences version 16. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data.

RESULTS

Women aged 35 years and above constituted 104 (5.73%) of the total deliveries of study period. Most were multigravida 72 (69.23%) and 23 (22.12%) had preterm delivery. Rate of caesarean section were higher in advance maternal age 69 (66.35%). Maternal complications such as Hypertensive disorder of pregnancy 9 (8.65%), and mal-presentation 15 (14.42%) were higher among them. Perinatal outcome in form of low birth weight 9 (8.65%) and perinatal death 5 (4.80%) were increased in those women.

CONCLUSIONS

From this study, it can be concluded that prevalence of advanced age at pregnancy was lower than study done in developed country but it was similar to study in India and is increasing in Nepal.

摘要

引言

高龄产妇妊娠时面临妊娠并发症和不良胎儿结局的风险。本研究旨在探讨一所教学医院高龄妊娠的流行情况。

方法

本研究为 2019 年 10 月至 2020 年 8 月在尼泊尔一家三级保健中心的妇产科进行的描述性横断面研究，研究获得了机构审查委员会的伦理批准（2019 年 9 月 3 日，编号 266），并获得了患者的知情同意。采用便利抽样法，选择所有≥35 岁且妊娠 28 周以上且无任何慢性疾病的患者。使用社会科学统计软件包 16 版进行数据和描述性分析，计算 95%置信区间的点估计值，并对二项数据进行频率和百分比计算。

结果

研究期间≥35 岁的产妇占总分娩人数的 104 人（5.73%）。她们大多为多产妇 72 人（69.23%），23 人（22.12%）早产。高龄产妇的剖宫产率较高，为 69 人（66.35%）。其中，母体并发症如妊娠高血压疾病 9 例（8.65%）、胎位不正 15 例（14.42%）较高。这些产妇的围产儿结局表现为低出生体重儿 9 例（8.65%）和围产儿死亡 5 例（4.80%）。