The Matilda Centre for Research in Mental Health and Substance Use Level 6, University of Sydney, Sydney, Australia.
Department of Psychiatry, Université de Montréal, Montreal, Quebec, Canada; Institute of Psychiatry, Kings College London, London, United Kingdom.
Prev Med. 2021 Dec;153:106794. doi: 10.1016/j.ypmed.2021.106794. Epub 2021 Sep 8.
This is the first study to investigate the effectiveness of Preventure, a selective personality-targeted prevention program, in reducing the uptake of tobacco smoking over a three-year period in adolescence. A cluster randomised controlled trial was conducted to assess the effectiveness of Preventure. Schools were block randomised to either the Preventure group (n = 7 schools) or the Control group (n = 7 schools) and students were assessed at five time points (baseline, 6-, 12-, 24- and 36-months post-baseline) on measures of tobacco use, intentions to use and self-efficacy to resist peer pressure to smoke tobacco. Intervention effects were estimated using mixed models to account for the hierarchical data structure. Exploratory analyses assessed intervention effects among internalising and externalising personality traits. This trial is registered with the Australian New Zealand Clinical Trials Registry (ACTRN12612000026820; www.anzctr.org.au). A total of 1005 adolescents (mean age: 13.4 years, SD = 0.47) attending 14 Australian schools in February 2012 were recruited to the study. Relative to students in Control schools, students in Preventure schools were less likely to report recent tobacco use (OR = 0.66 95% CI = 0.50, 0.87) and intentions to use tobacco in the future (OR = 0.77 95% CI = 0.60, 0.97) over the three-year follow-up. Students in Preventure schools with internalising personality traits had a greater increase in their likelihood to report high self-efficacy to resist peer pressure to smoke sustained three-years post program delivery (OR = 1.85 95% CI = 1.0, 3.4). Findings from this study support the use of selective personality-targeted preventive interventions in reducing tobacco smoking during adolescence.
这是第一项研究，旨在调查 Preventure 的有效性，Preventure 是一种选择性人格靶向预防计划，旨在减少青少年三年内吸烟的发生率。采用集群随机对照试验评估 Preventure 的有效性。学校按预防组（n=7 所学校）和对照组（n=7 所学校）进行分组，并在 5 个时间点（基线、6 个月、12 个月、24 个月和 36 个月）评估学生的吸烟使用、使用意向和抵制同伴吸烟压力的自我效能感。使用混合模型估计干预效果，以解释数据的层级结构。探索性分析评估了内在和外在人格特质的干预效果。该试验在澳大利亚和新西兰临床试验注册中心（ACTRN12612000026820；www.anzctr.org.au）注册。共有 1005 名青少年（平均年龄：13.4 岁，标准差=0.47）参加了 2012 年 2 月在澳大利亚 14 所学校开展的这项研究。与对照组的学生相比，预防组的学生在三年内报告最近吸烟的可能性较小（OR=0.66 95%CI=0.50，0.87），未来使用烟草的意向也较小（OR=0.77 95%CI=0.60，0.97）。具有内向人格特质的预防组学生在计划实施后三年内，报告抵制同伴吸烟压力的高自我效能感的可能性更大（OR=1.85 95%CI=1.0，3.4）。这项研究的结果支持在青少年时期使用选择性人格靶向预防干预来减少吸烟。
