Department of Nursing, School of Nursing and Midwifery, Babol University of Medical Sciences, Babol, Iran.
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Operating Room Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.
Sleep Med. 2021 Nov;87:8-19. doi: 10.1016/j.sleep.2021.07.017. Epub 2021 Jul 31.
Recent studies have reported inconclusive results regarding the potential effects of Rosa damascena on sleep quality. Therefore, this review aimed to summarize the findings of parallel-group and cross-over randomized controlled trials (RCTs) on the effects of aromatherapy and oral intake of Rosa damascena on adults' sleep quality.
The electronic data sources of PubMed, Scopus, Web of Science Core Collection, Embase, CENTRAL, ProQuest, CINAHL, SID, and MagIran were searched from inception to June 30, 2021. Out of 1341 publications found in the initial search, 10 RCTs were considered eligible for this review. The Cochrane risk-of-bias assessment tool was used to evaluate the risk of bias. Sufficient data were statistically pooled by a random-effects model using Stata software (version 11.2); otherwise, a narrative summary was presented.
Based on the systematic review, the inhalation and oral intake of Rosa damascena could improve some sleep-related outcomes. The pooled analysis of seven effect sizes revealed that inhalation aromatherapy with Rosa damascena significantly improved sleep quality (standardized mean difference: 2.24; 95% confidence interval: 1.01-3.48; P < 0.001). Most RCTs had fair methodological quality, and two RCTs reported the adverse effects of treatment, including headache, nausea, vomiting, and frequent sneezing.
The administration of Rosa damascena seems to be a promising approach in complementary and alternative medicine for the improvement of adults' sleep quality. However, considering the fair methodological quality of most RCTs and reported adverse effects, it is required to perform further high-quality RCTs to draw an evidence-based conclusion on the use of Rosa damascena for the improvement of adults' sleep quality.
CRD42020211778.
最近的研究报告称，关于大马士革玫瑰对睡眠质量的潜在影响，结果尚无定论。因此，本综述旨在总结平行组和交叉随机对照试验（RCT）关于芳香疗法和口服大马士革玫瑰对成年人睡眠质量影响的发现。
从建库到 2021 年 6 月 30 日，检索了 PubMed、Scopus、Web of Science 核心合集、Embase、CENTRAL、ProQuest、CINAHL、SID 和 MagIran 等电子数据库。在最初的搜索中发现了 1341 篇出版物，其中 10 项 RCT 被认为符合本综述的纳入标准。使用 Cochrane 偏倚风险评估工具评估偏倚风险。使用 Stata 软件（版本 11.2）通过随机效应模型对足够的数据进行统计学合并；否则，采用叙述性总结。
基于系统评价，吸入和口服大马士革玫瑰可以改善一些与睡眠相关的结果。对七个效应量的汇总分析表明，吸入大马士革玫瑰的芳香疗法显著改善了睡眠质量（标准化均数差：2.24；95%置信区间：1.01-3.48；P<0.001）。大多数 RCT 的方法学质量为中等，有两项 RCT 报告了治疗的不良反应，包括头痛、恶心、呕吐和频繁打喷嚏。
在补充和替代医学中，给予大马士革玫瑰似乎是一种很有前途的方法，可以改善成年人的睡眠质量。然而，考虑到大多数 RCT 的中等方法学质量和报告的不良反应，有必要进行进一步的高质量 RCT，以得出关于使用大马士革玫瑰改善成年人睡眠质量的循证结论。
PROSPERO 注册号：CRD42020211778。
