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头颈部毛霉菌病——COVID-19 大流行中的新兴健康问题。牙医的观点。

Mucormycosis in head and neck area - the emerging health problem in COVID-19 pandemic. The perspective of a dental practitioner.

机构信息

Chair of Pharmacology, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Folia Med Cracov. 2021;61(2):117-127. doi: 10.24425/fmc.2021.137228.

DOI:10.24425/fmc.2021.137228
PMID:34510169
Abstract

Mucormycosis is an invasive fungal disease caused by saprophytic molds and is characterized by a fulminant course and high mortality. Reported increase of disease cases and more frequent mucormycosis superinfections in COVID-19 patients are of a serious concern. Head and neck area is the most typical location of mucormycosis and often the first symptoms are eminent in oral cavity, therefore a dentist may be the first healthcare practitioner to recognize signs of this dangerous and potentially fatal disease. Urgent diagnosis and implementation of appropriate treatment are essential for the patient's survival. The dentist's participation in postoperative care is necessary and due to the destructive nature of radical surgical treatment, prosthetic rehabilitation is required to improve the patient's function and quality of life. Furthermore the vigilance of dentists will also allow early recognition of frequent recurrences of this insidious infection.

摘要

毛霉病是一种由腐生霉菌引起的侵袭性真菌病,其特点是病程迅猛,死亡率高。COVID-19 患者中报道的病例增加和更频繁的毛霉病合并感染令人严重关切。头颈部是毛霉病最典型的部位,口腔往往是最早出现症状的部位,因此牙医可能是第一个发现这种危险且潜在致命疾病迹象的医疗保健从业者。紧急诊断和实施适当的治疗对患者的生存至关重要。牙医参与术后护理是必要的,并且由于根治性手术治疗的破坏性,需要进行修复治疗以改善患者的功能和生活质量。此外,牙医的警惕性也将有助于早期发现这种隐匿性感染的频繁复发。

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