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先天性脊柱侧凸患者的融合手术年龄较大是延长住院时间、增加估计失血量、增加融合节段和增加医疗费用的危险因素:一项回顾性研究。

Older fusion-surgery age in congenital scoliosis patients is a risk factor for extended length of stay, more estimated blood loss, longer fused segments and higher medical costs: a retrospective study.

机构信息

Departments of Orthopaedic Surgery, Peking Union Medical College Hospital (PUMCH), 1st Shuai Fu Yuan Hutong, Dongcheng District, 100730, Beijing, People's Republic of China.

出版信息

BMC Musculoskelet Disord. 2021 Sep 12;22(1):779. doi: 10.1186/s12891-021-04650-6.

Abstract

BACKGROUND

Contradictory opinions about whether early correction and fusion surgeries should be performed for congenital scoliosis (CS) patients at a young age exist. The objectives of this study were to analyze the association between patient characteristics and fusion-surgery outcomes in CS patients treated with spinal correction and fusion surgeries and to report risk factors for extended length of stay (LOS), more estimated blood loss (EBL), longer fused segments and higher medical costs.

METHODS

We analyzed data of 1,207 CS inpatients treated with fusion surgeries in our institute from January 2010 - December 2019. All patients underwent spinal X-ray, CT, MRI, echocardiogram and urogenital ultrasound. We analyzed demographic and clinical information and outcome measures, including LOS, EBL, fused segments and medical costs.

RESULTS

Age at fusion (OR = 1.053; p < 0.001), musculoskeletal defects (OR = 1.670; p = 0.004) and thoracic deformity (OR = 1.519; p = 0.03) were risk factors for extended LOS. Age at fusion (OR = 1.117; p < 0.001), male sex (OR = 1.813; p < 0.001), mixed defects (OR = 1.662; p = 0.027) and failure of formation (OR = 1.718; p = 0.021) were risk factors for more EBL. Age at fusion (OR = 1.213; p < 0.001) was a risk factor for longer fused segments. Age at fusion (OR = 1.091; p < 0.001) and thoracic deformity (OR = 1.853; p = 0.004) were risk factors for higher medical costs.

CONCLUSIONS

We found that older age at fusion in CS patients is a risk factor for extended LOS, more EBL, longer fused segments and higher medical costs with the risk increasing by 5-21 % for each year of age. Other identified risk factors include thoracic deformity for extended LOS; longer fused segments, higher medical costs, and musculoskeletal defects for extended LOS; and CS type (FF and MD) and sex (male) for more EBL.

摘要

背景

对于先天性脊柱侧凸(CS)患者,是否应在幼年进行早期矫正和融合手术,存在相互矛盾的观点。本研究的目的是分析脊柱矫正和融合手术后 CS 患者的患者特征与融合手术结果之间的关系,并报告延长住院时间(LOS)、更多估计失血量(EBL)、更长融合节段和更高医疗费用的风险因素。

方法

我们分析了 2010 年 1 月至 2019 年 12 月在我院接受融合手术的 1207 例 CS 住院患者的数据。所有患者均接受脊柱 X 线、CT、MRI、超声心动图和泌尿生殖系统超声检查。我们分析了人口统计学和临床信息以及结果测量指标,包括 LOS、EBL、融合节段和医疗费用。

结果

融合时年龄(OR=1.053;p<0.001)、肌肉骨骼缺陷(OR=1.670;p=0.004)和胸段畸形(OR=1.519;p=0.03)是延长 LOS 的危险因素。融合时年龄(OR=1.117;p<0.001)、男性(OR=1.813;p<0.001)、混合缺陷(OR=1.662;p=0.027)和形成失败(OR=1.718;p=0.021)是增加 EBL 的危险因素。融合时年龄(OR=1.213;p<0.001)是延长融合节段的危险因素。融合时年龄(OR=1.091;p<0.001)和胸段畸形(OR=1.853;p=0.004)是增加医疗费用的危险因素。

结论

我们发现 CS 患者融合时年龄较大是延长 LOS、增加 EBL、延长融合节段和增加医疗费用的危险因素,每增加 1 岁,风险增加 5-21%。其他确定的危险因素包括胸段畸形与延长 LOS 相关;更长的融合节段、更高的医疗费用、肌肉骨骼缺陷与延长 LOS 相关;CS 类型(FF 和 MD)和性别(男性)与更多的 EBL 相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7824/8436475/8ae829255921/12891_2021_4650_Fig1_HTML.jpg

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