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内感受与强迫症:当前证据综述及未来方向

Interoception and Obsessive-Compulsive Disorder: A Review of Current Evidence and Future Directions.

作者信息

Bragdon Laura B, Eng Goi Khia, Belanger Amanda, Collins Katherine A, Stern Emily R

机构信息

Department of Psychiatry, New York University School of Medicine, New York, NY, United States.

Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, United States.

出版信息

Front Psychiatry. 2021 Aug 25;12:686482. doi: 10.3389/fpsyt.2021.686482. eCollection 2021.

Abstract

Disrupted interoceptive processes are present in a range of psychiatric conditions, and there is a small but growing body of research on the role of interoception in obsessive-compulsive disorder (OCD). In this review, we outline dimensions of interoception and review current literature on the processing of internal bodily sensations within OCD. Investigations in OCD utilizing objective measures of interoception are limited and results mixed, however, the subjective experience of internal bodily sensations appears to be atypical and relate to specific patterns of symptom dimensions. Further, neuroimaging investigations suggest that interoception is related to core features of OCD, particularly sensory phenomena and disgust. Interoception is discussed in the context of treatment by presenting an overview of existing interventions and suggesting how modifications aimed at better targeting interoceptive processes could serve to optimize outcomes. Interoception represents a promising direction for multi-method research in OCD, which we expect, will prove useful for improving current interventions and identifying new treatment targets.

摘要

内感受过程紊乱存在于一系列精神疾病中,关于内感受在强迫症(OCD)中的作用,虽研究数量不多,但在不断增加。在本综述中,我们概述了内感受的维度,并回顾了当前关于强迫症患者内部身体感觉处理的文献。利用内感受客观测量方法对强迫症的研究有限,结果也参差不齐,然而,内部身体感觉的主观体验似乎是非典型的,且与特定的症状维度模式相关。此外,神经影像学研究表明,内感受与强迫症的核心特征有关,尤其是感觉现象和厌恶感。通过概述现有干预措施并提出如何针对内感受过程进行更好的调整以优化治疗效果,在内感受与治疗的背景下进行了讨论。内感受是强迫症多方法研究的一个有前景的方向,我们预计这将有助于改进当前的干预措施并确定新的治疗靶点。

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