Melikyan A A, Menkov A V
Surgeon, Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashko, 190 Rodionova St., Nizhny Novgorod, 603126, Russia.
Professor, Department of General, Operative Surgery and Topographic Anatomy named after A.I. Kozhevnikov, Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
Sovrem Tekhnologii Med. 2020;12(2):101-108. doi: 10.17691/stm2020.12.2.13.
This review summarizes the results of studies concerning the problem of post-surgical hypoparathyroidism, a common complication of thyroid gland surgery, decreasing the quality of life in patients and, in some cases, leading to disability. A search for publications was carried out in electronic databases Web of Science, Scopus, Academic Search Complete (EBSCO), eLIBRARY, using keywords. The search depth was 7-10 years. Prevalence of post-surgical hypoparathyroidism was evaluated, the pathogenetic causes of the disease development, its clinical forms, methods of diagnosis and treatment were studied. It has been found that there is no single algorithm for analyzing the prognostic factors for the development of this pathological condition. It is emphasized that drug therapy of post-surgical hypoparathyroidism has a number of adverse effects. Therefore, the issues of prevention and surgical correction are of particular relevance. However, controversial opinions of contemporary authors about their clinical effectiveness determine the scientific and practical significance of further research on these issues.
本综述总结了有关术后甲状旁腺功能减退问题的研究结果,这是甲状腺手术的常见并发症,会降低患者的生活质量,在某些情况下还会导致残疾。使用关键词在电子数据库Web of Science、Scopus、Academic Search Complete(EBSCO)、eLIBRARY中进行文献检索。检索深度为7 - 10年。评估了术后甲状旁腺功能减退的患病率,研究了该疾病发生发展的致病原因、临床类型、诊断和治疗方法。结果发现,对于分析这种病理状况发生发展的预后因素,没有单一的算法。强调术后甲状旁腺功能减退的药物治疗有许多不良反应。因此,预防和手术矫正问题具有特别重要的意义。然而,当代作者对其临床效果存在争议的观点决定了对这些问题进行进一步研究的科学和实际意义。