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外耳道角化棘皮瘤。

Keratoacanthoma in the External Auditory Canal.

作者信息

Ash Javier, Limbu Raju, Alexander Victoria, Selvadurai David

机构信息

General Surgery, Princess Alexandra Hospital, Harlow, GBR.

Otolaryngology, St. George's University Hospital, London, GBR.

出版信息

Cureus. 2021 Aug 4;13(8):e16873. doi: 10.7759/cureus.16873. eCollection 2021 Aug.

DOI:10.7759/cureus.16873
PMID:34513448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8411997/
Abstract

A 63-year-old male presented with a prolonged history of bilateral ear discharge, otalgia, and hearing loss. The patient required a significant number of investigations prior to obtaining a diagnosis. Subsequent investigations identified keratoacanthoma affecting the external ear canal (EAC). There has been no case report of keratoacanthoma within the EAC till now. The only risk factor identified for the development of keratoacanthoma, in this case, was the frequent use of earbuds and subsequent long-term trauma associated with a retained bud. The histology of keratoacanthoma is difficult to differentiate from that of squamous cell carcinoma but this is essential for the ear, nose, throat (ENT) multi-disciplinary team.

摘要

一名63岁男性,有双侧耳溢液、耳痛和听力损失的长期病史。在获得诊断之前,该患者需要进行大量检查。随后的检查发现外耳道(EAC)患有角化棘皮瘤。迄今为止,尚无外耳道角化棘皮瘤的病例报告。在该病例中,确定的角化棘皮瘤发生的唯一风险因素是频繁使用耳塞以及随后因耳塞残留而导致的长期创伤。角化棘皮瘤的组织学很难与鳞状细胞癌相区分,但这对耳鼻喉科(ENT)多学科团队来说至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdf9/8411997/f119fe015325/cureus-0013-00000016873-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdf9/8411997/f119fe015325/cureus-0013-00000016873-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cdf9/8411997/f119fe015325/cureus-0013-00000016873-i01.jpg

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引用本文的文献

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Surgical excision of a giant solitary keratoacanthoma in the cheek: a case report and literature review.颊部巨大孤立性角化棘皮瘤的手术切除:一例报告并文献复习
AME Case Rep. 2023 Dec 1;8:7. doi: 10.21037/acr-23-100. eCollection 2024.

本文引用的文献

1
Keratoacanthoma of the Nasal Septum Secondary to Ranibizumab Use.使用雷珠单抗后继发鼻中隔角棘皮瘤
Case Rep Pathol. 2017;2017:8257590. doi: 10.1155/2017/8257590. Epub 2017 May 11.
2
Cutaneous neuroendocrine carcinoma of the external auditory canal: a case report and review of the literature.外耳道皮肤神经内分泌癌:一例报告并文献复习
Case Rep Otolaryngol. 2012;2012:941065. doi: 10.1155/2012/941065. Epub 2012 Aug 5.
3
Differentiating keratoacanthoma from squamous cell carcinoma by the use of apoptotic and cell adhesion markers.
通过使用凋亡和细胞粘附标记物鉴别角化棘皮瘤与鳞状细胞癌。
Histopathology. 2005 Aug;47(2):170-8. doi: 10.1111/j.1365-2559.2005.02155.x.
4
Keratoacanthoma developing in sites of previous trauma: a report of two cases and review of the literature.先前创伤部位发生的角化棘皮瘤:两例报告及文献复习
J Am Acad Dermatol. 2003 Feb;48(2 Suppl):S35-8. doi: 10.1067/mjd.2003.114.
5
A case of giant keratoacanthoma of the auricle.
Auris Nasus Larynx. 2000 Apr;27(2):185-8. doi: 10.1016/s0385-8146(99)00073-5.
6
Keratoacanthoma.角化棘皮瘤
J Am Acad Dermatol. 1994 Jan;30(1):1-19; quiz 20-2. doi: 10.1016/s0190-9622(94)70001-x.