腹腔镜袖状胃切除术中单核细胞与高密度脂蛋白胆固醇比值与体重过度减轻的关系
Relationship between monocyte-to-high-density lipoprotein cholesterol ratio and excess weight loss in laparoscopic sleeve gastrectomy.
作者信息
Serin Sibel Ocak, Sisik Abdullah, Basak Fatih
机构信息
Department of Internal Medicine, University of Health Sciences, Umraniye Training & Research Hospital, Istanbul, 34760, Turkey.
Department of General Surgery, University of Health Sciences, Umraniye Training & Research Hospital, Istanbul, 34760, Turkey.
出版信息
Biomark Med. 2021 Oct;15(15):1367-1375. doi: 10.2217/bmm-2021-0244. Epub 2021 Sep 13.
The present study evaluates the relationship between the monocyte-to-high-density lipoprotein cholesterol ratio (MHR) and the percentage of excess weight loss (%EWL) in patients undergoing laparoscopic sleeve gastrectomy. This prospective cohort study evaluated 125 patients who underwent laparoscopic sleeve gastrectomy. The MHR before and at 6 months after surgery were compared in patients with <50 and ≥50 %EWL. The MHR was lower in patients with a %EWL of <50 than in patients with a %EWL of ≥50 (p = 0.019). The decrease in the MHR at postoperative 6 months was more remarkable in patients with a %EWL of ≥50 (p < 0.001). The present study suggests that MHR decreased more remarkably at postoperative 6 months in patients with high %EWL, predicting a decrease in cardiovascular risk.
本研究评估了接受腹腔镜袖状胃切除术患者的单核细胞与高密度脂蛋白胆固醇比值（MHR）与超重减轻百分比（%EWL）之间的关系。这项前瞻性队列研究评估了125例接受腹腔镜袖状胃切除术的患者。比较了%EWL<50%和≥50%的患者术前及术后6个月的MHR。%EWL<50%的患者MHR低于%EWL≥50%的患者（p=0.019）。术后6个月，%EWL≥50%的患者MHR下降更为显著（p<0.001）。本研究表明，%EWL高的患者术后6个月MHR下降更为显著，预示着心血管风险降低。
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