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Retrospective analysis of the effects of a hyaluronic-based gum gel to counteract signs and symptoms of teething in infants.

作者信息

DI Pierro Francesco, Bertuccioli Alexander, Donato Guido, Spada Cristiano

机构信息

Scientific Department, Velleja Research, Milan, Italy -

Department of Digestive Endoscopy, Fondazione Poliambulanza, Brescia, Italy -

出版信息

Minerva Pediatr (Torino). 2022 Apr;74(2):101-106. doi: 10.23736/S2724-5276.21.06550-2. Epub 2021 Sep 13.

DOI:10.23736/S2724-5276.21.06550-2
PMID:34515447
Abstract

BACKGROUND

Teething discomfort is a widespread disorder affecting a very high percentage of infants. It creates anxiety in parents, who look for help in pediatric clinics. The use of hyaluronic acid gels has been shown in the last 20 years to be an effective tool, generally devoid of side effects, in reducing oral mucosal inflammation in adults. Recently, such results have also been confirmed in infants affected by teething.

METHODS

From our routine practice results, we have retrospectively reported the efficacy and the safety profile of Bonjela Soothing Teething Gel (Bonkela, Reckitt Benckiser, UK), a teething gel capable of addressing in a significant way this infant complaint, which improves all the clinical outcomes used in these types of study to describe the clinical condition of infants.

RESULTS

The time×group interaction showed significant differences in unexplained cry, irritability, inappetence, salivation and gum redness (P<0.01 for all comparisons), with lower Likert scores in the treated group respect to the control one.

CONCLUSIONS

The treatment with Bonjela Soothing Teething Gel contributed to reduce some common symptoms of teething, in comparison to the standard use of a teething ring alone.

摘要

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