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人胎儿会厌黏膜的电子显微镜研究。

Electron microscopic study on the epiglottic mucosa in human fetuses.

作者信息

Sakai N, Saito J, Suenaga T, Tanaka K, Terayama Y

机构信息

Department of Otorhinolaryngology, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

Auris Nasus Larynx. 1987;14(3):177-85. doi: 10.1016/s0385-8146(87)80019-6.

Abstract

The differentiation of the epiglottic mucosa in human fetuses has so far been studied only by light microscopy. So, we studied the epiglottic mucosa in human fetuses (at gestational ages from the 7th to 21st week) by scanning (SEM) and transmission electron microscopies (TEM), and could disclose more detailed features of cellular differentiation of this mucosa. These results and the review of the literatures lead to the following conclusions: 1. Primary cilia appeared in the epiglottic mucosa around the 7th week of gestation. 2. Ciliated cells and the stratified squamous epithelium of the lingual surface appeared at the similar period as reported by others, but our study revealed that the squamous cells are immature even at the 21st week. 3. Glycogen granules in non-ciliated cells decreased paralleling the differentiation of the cells, suggesting that they provide a source of energy necessary for the cell differentiation.

摘要

迄今为止,仅通过光学显微镜对人类胎儿会厌黏膜的分化进行了研究。因此,我们通过扫描电子显微镜(SEM)和透射电子显微镜(TEM)对人类胎儿(孕龄7至21周)的会厌黏膜进行了研究,从而能够揭示该黏膜细胞分化的更详细特征。这些结果以及文献综述得出以下结论:1. 妊娠约7周时,会厌黏膜中出现初级纤毛。2. 纤毛细胞和舌面的复层鳞状上皮在与其他人报道的相似时期出现,但我们的研究表明,即使在孕21周时鳞状细胞仍不成熟。3. 非纤毛细胞中的糖原颗粒随着细胞分化而减少,这表明它们为细胞分化提供了必要的能量来源。

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