Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Department of Child's and Adolescent's Oral Health, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Head Neck. 2021 Nov;43(11):3562-3571. doi: 10.1002/hed.26854. Epub 2021 Sep 13.
To evaluate the frequency and analyze demographic and clinical characteristics of individuals with a histopathological diagnosis of oral lymphatic malformations (OLMs).
A multicenter study was performed, collecting biopsy record data from a consortium of Brazilian Oral and Maxillofacial Pathology Centers. A review was also conducted to compare this data with cases already available in the literature.
This study retrieved 208 cases of OLM in the multicenter study and 1035 cases in the literature review. In both, OLMs affected male and female individuals equally, with the most affected site being the tongue. Individuals ≥60 years of age were uncommonly affected. Symptomatic and larger lesions were more commonly reported in the literature review.
This study comprises the largest sample of OLMs to date. OLMs are rare conditions, without sex predilection. The elderly proved to be less frequently affected, and the tongue is the most commonly affected site.
评估具有口腔淋巴畸形（OLM）组织病理学诊断的个体的频率，并分析其人口统计学和临床特征。
进行了一项多中心研究，从巴西口腔颌面病理学中心联盟收集活检记录数据。还进行了一次文献复习，以比较这些数据与已有的文献病例。
本研究在多中心研究中检索到 208 例 OLM，在文献复习中检索到 1035 例 OLM。在多中心研究和文献复习中，OLM 均影响男女比例相等，最常受累的部位是舌头。≥60 岁的个体很少受影响。在文献复习中，更多地报告了有症状和更大的病变。
本研究是迄今为止 OLM 最大的样本。OLM 是罕见的疾病，无性别倾向。老年人受影响的频率较低，最常受累的部位是舌头。
