Asghari Ali, Adhami Ghazaaleh, Shariatzadeh Seyyed Ali, Kordi Bahareh, Anvari Davood, Shams Morteza, Majidiani Hamidreza, Darvishi Mohammad Mahdi
Department of Medical Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Veterinary Pathobiology, Faculty of Veterinary Medicine, Islamic Azad University of Sanandaj, Sanandaj, Iran.
Parasitol Res. 2021 Nov;120(11):3633-3644. doi: 10.1007/s00436-021-07309-2. Epub 2021 Sep 14.
Diverse Onchocerca species are present mostly parasitizing ungulates, with the exception of Onchocerca volvulus (O. volvulus) in humans and O. lupi in canids and cats. The human cases due to the O. lupi have been more highlighted during last years. So, the present review was performed to determine the detailed characteristics of confirmed human O. lupi case reports documented worldwide. Hence, a systematic search was done using English international databases (Scopus, PubMed, Web of Science, Embase, ProQuest, and Google Scholar). Totally, 14 confirmed human cases were documented during the last decade, mostly from the USA and Turkey with 7 and 3 cases, respectively. Most cases (7 individuals) were male with the age range of 22-month-old to 54-year-old. The parasite was frequently isolated from the right eye (5 cases), followed by the left eye (4 cases), cervical spinal canal (3 cases), scalp, and right forearm (one case each). Molecular identification of the isolated agent was the preferred way of diagnosis in most cases (9 records). In conclusion, human O. lupi cases have been more highlighted in recent years, whether due to the improved diagnostics and/or host-switching phenomenon, and both veterinarians and healthcare authorities should be alerted.
多种盘尾丝虫主要寄生于有蹄类动物，人类的旋盘尾丝虫和犬科动物及猫的狼盘尾丝虫除外。近年来，由狼盘尾丝虫引起的人类病例受到了更多关注。因此，本综述旨在确定全球范围内已确诊的人类狼盘尾丝虫病例报告的详细特征。为此，我们使用英文国际数据库（Scopus、PubMed、Web of Science、Embase、ProQuest和谷歌学术）进行了系统检索。在过去十年中，共记录了14例确诊的人类病例，其中大多数来自美国和土耳其，分别为7例和3例。大多数病例（7例）为男性，年龄范围为22个月至54岁。寄生虫常从右眼分离出（5例），其次是左眼（4例）、颈椎管（3例）、头皮和右前臂（各1例）。在大多数病例（9份记录）中，对分离出的病原体进行分子鉴定是首选的诊断方法。总之，近年来人类狼盘尾丝虫病例受到了更多关注，这可能是由于诊断方法的改进和/或宿主转换现象，兽医和卫生保健当局都应提高警惕。
