• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

精神科药物、镇痛药和抗癫痫药在慢性瘙痒中的作用

The Role of Psychiatric, Analgesic, and Antiepileptic Medications in Chronic Pruritus.

作者信息

Patel Parth, Patel Keshav, Pandher Karan, Tareen Ruqiya Shama

机构信息

Dermatology, Lake Erie College of Osteopathic Medicine, San Diego, USA.

Internal Medicine, University of Illinois Chicago, Kalamazoo, USA.

出版信息

Cureus. 2021 Aug 17;13(8):e17260. doi: 10.7759/cureus.17260. eCollection 2021 Aug.

DOI:10.7759/cureus.17260
PMID:34522555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8425105/
Abstract

Chronic pruritus is a complex yet prevalent concern without a gold standard treatment. The mainstay therapy for chronic pruritus includes topical ointments such as corticosteroids, capsaicin, local anesthetics, antihistamines, and immunomodulators. There are many different subtypes of chronic pruritus, and each unique subtype may benefit from specialized treatments. This review article sheds light on the role of psychiatric, analgesic, and antiepileptic medications in chronic pruritus. We believe that further large-scale studies are needed to determine the true effectiveness of these medications in treating chronic pruritus.

摘要

慢性瘙痒是一个复杂但普遍存在的问题，目前尚无金标准治疗方法。慢性瘙痒的主要治疗方法包括外用软膏，如皮质类固醇、辣椒素、局部麻醉剂、抗组胺药和免疫调节剂。慢性瘙痒有许多不同的亚型，每种独特的亚型可能从专门治疗中获益。这篇综述文章阐明了精神科、镇痛和抗癫痫药物在慢性瘙痒中的作用。我们认为需要进一步的大规模研究来确定这些药物治疗慢性瘙痒的真正有效性。

相似文献

1
The Role of Psychiatric, Analgesic, and Antiepileptic Medications in Chronic Pruritus.精神科药物、镇痛药和抗癫痫药在慢性瘙痒中的作用
Cureus. 2021 Aug 17;13(8):e17260. doi: 10.7759/cureus.17260. eCollection 2021 Aug.
2
Antidepressants as antipruritic agents: A review.抗抑郁药作为止痒药：综述。
Eur Neuropsychopharmacol. 2018 Mar;28(3):341-352. doi: 10.1016/j.euroneuro.2018.01.007. Epub 2018 Feb 16.
3
A practical review and update on the management of pruritus sine materia.无明显皮肤损害性瘙痒症管理的实用综述与更新
Cutis. 2008 Sep;82(3):187-94.
4
Cromolyn sodium: a potential therapy for uremic pruritus?色甘酸钠：一种治疗尿毒症瘙痒症的潜在疗法？
Hemodial Int. 2006 Apr;10(2):189-92. doi: 10.1111/j.1542-4758.2006.00093.x.
5
[Antihistamines for treating pruritus : The end of an era?].[抗组胺药治疗瘙痒症：一个时代的终结？]
Hautarzt. 2020 Jul;71(7):525-527. doi: 10.1007/s00105-020-04617-z.
6
Mirtazapine for the Treatment of Chronic Pruritus.米氮平治疗慢性瘙痒症
Medicines (Basel). 2019 Jul 6;6(3):73. doi: 10.3390/medicines6030073.
7
Aprepitant for the Treatment of Chronic Refractory Pruritus.阿瑞匹坦治疗慢性难治性瘙痒症。
Biomed Res Int. 2017;2017:4790810. doi: 10.1155/2017/4790810. Epub 2017 Sep 19.
8
Uremic pruritus.尿毒症瘙痒
Am J Health Syst Pharm. 1996 Sep 15;53(18):2159-70; quiz 2215-6. doi: 10.1093/ajhp/53.18.2159.
9
Evaluation of Treatments for Pruritus in Epidermolysis Bullosa.大疱性表皮松解症瘙痒治疗的评估
Pediatr Dermatol. 2015 Sep-Oct;32(5):628-34. doi: 10.1111/pde.12486. Epub 2014 Dec 29.
10
Psychiatric medications for the treatment of pruritus.用于治疗瘙痒症的精神科药物。
Psychosom Med. 2007 Dec;69(9):970-8. doi: 10.1097/PSY.0b013e3181572799. Epub 2007 Nov 8.

本文引用的文献

1
Treatment Refractory Brachioradial Pruritus Treated with Topical Amitriptyline and Ketamine.外用阿米替林和氯胺酮治疗难治性肱桡肌瘙痒症
Cureus. 2019 Jul 10;11(7):e5117. doi: 10.7759/cureus.5117.
2
Mirtazapine for the Treatment of Chronic Pruritus.米氮平治疗慢性瘙痒症
Medicines (Basel). 2019 Jul 6;6(3):73. doi: 10.3390/medicines6030073.
3
Prurigo successfully treated with duloxetine hydrochloride.盐酸度洛西汀成功治疗痒疹。
Australas J Dermatol. 2019 Aug;60(3):237-239. doi: 10.1111/ajd.12996. Epub 2019 Jan 24.
4
The behavioral study on the interactive aggravation between pruritus and depression.瘙痒与抑郁的相互加重的行为学研究。
Brain Behav. 2018 Jun;8(6):e00964. doi: 10.1002/brb3.964. Epub 2018 May 1.
5
Psychogenic Pruritus and Its Management.精神性瘙痒及其管理
Dermatol Clin. 2018 Jul;36(3):309-314. doi: 10.1016/j.det.2018.02.015.
6
Selective serotonin reuptake inhibitors for the treatment of chronic pruritus.用于治疗慢性瘙痒的选择性5-羟色胺再摄取抑制剂
J Dermatolog Treat. 2018 Dec;29(8):812-814. doi: 10.1080/09546634.2018.1456639. Epub 2018 Apr 12.
7
Use of oral antidepressants in patients with chronic pruritus: A systematic review.慢性瘙痒患者使用口服抗抑郁药：系统评价。
J Am Acad Dermatol. 2017 Dec;77(6):1068-1073.e7. doi: 10.1016/j.jaad.2017.08.025. Epub 2017 Oct 21.
8
Efficacy of hydralazine and valproate in cutaneous T-cell lymphoma, a phase II study.肼屈嗪与丙戊酸盐治疗皮肤T细胞淋巴瘤的疗效：一项II期研究
Expert Opin Investig Drugs. 2017 Apr;26(4):481-487. doi: 10.1080/13543784.2017.1291630. Epub 2017 Feb 15.
9
Duloxetine for treating painful neuropathy, chronic pain or fibromyalgia.度洛西汀用于治疗疼痛性神经病变、慢性疼痛或纤维肌痛。
Cochrane Database Syst Rev. 2014 Jan 3;2014(1):CD007115. doi: 10.1002/14651858.CD007115.pub3.
10
Pruritus: management algorithms and experimental therapies.瘙痒：管理算法与实验性疗法
Semin Cutan Med Surg. 2011 Jun;30(2):127-37. doi: 10.1016/j.sder.2011.05.001.