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血液流变学紊乱在下肢深静脉术后血栓形成中的作用

[The role of hemorheological disorders in the development of postoperative thrombosis of the deep veins of the legs].

作者信息

Aleksandrova N P, Petukhov E B, Golovina L A, Karalkin A V

出版信息

Vestn Khir Im I I Grek. 1987 Oct;139(10):98-102.

PMID:3452273
Abstract

The interrelationship between hemorheological alterations (hyperviscosity of blood, lower deformability of erythrocytes, elevated aggregation activity of thrombocytes) developing prior to and during operation and the development of intra- and postoperative thromboses of profound veins of lower extremities was studied by results of examination of 70 surgical patients. It was found that in 44% of the patients the initial phase of thrombosis can be diagnosed within the first 3 hours after operation. Risk factors of the development of thrombosis are high preoperative viscosity of blood, circulating thrombocyte aggregates, low fibrinolytic activity of plasma.

摘要

通过对70例外科手术患者的检查结果,研究了手术前及手术过程中出现的血液流变学改变(血液高粘度、红细胞变形性降低、血小板聚集活性升高)与下肢深静脉血栓形成及术后血栓形成之间的相互关系。结果发现,44%的患者在术后3小时内即可诊断出血栓形成的初始阶段。血栓形成的危险因素包括术前血液高粘度、循环血小板聚集体、血浆纤溶活性降低。

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